European Respiratory Society

Figure 3

Fri, 2021-07-09 16:43 -- admin
Summary: 
Proposed treatment algorithm for PAH–HIV. NO: nitric oxide; CCB: calcium channel blocker; NYHA: New York Heart Association; ERA: endothelin receptor antagonists; PDE-5: phosphodiesterase type-5. #: must be considered irrespective of the viral load or the CD4+ cell count; ¶: before considering treatment with oral anticoagulant, drug–drug interactions with protease inhibitors must be taken in account; +: contraindicated in the case of severe cirrhosis (Child–Pugh score C) or an increase in serum liver enzymes (alanine transaminase and aspartate aminotransferase) of more than three times the upper limit of normal; §: before considering treatment with PDE-5 inhibitor, drug–drug interactions with protease inhibitors must be taken into account; sildenafil and tadalafil are contraindicated with concomitant treatment with ritonavir. Reproduced and modified from [39, 66] with permission from the publishers.
Type: 
Figure
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Normal
Slug: 
F27
Highwire: Type: 
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Highwire: Variants: 
expansion
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Highwire: State: 
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