European Respiratory Society

Figure 1

Fri, 2021-07-09 16:24 -- admin
Summary: 
Relative impact of inherited and environmental factors on manifestation of cystic fibrosis (CF) disease as estimated by genetic modelling of monozygous CF twins, dizygous CF twins and CF sibling pairs. Covariance matrices of weight-for-height (WfH) % predicted and forced expiratory volume in 1 s (FEV1) % predicted were analysed by genetic modelling [13]. All CF pairs and the subgroup of Phe508del-CFTR (cystic fibrosis transmembrane conductance regulator) homozygotes were evaluated. Models were based on a linear combination of the four following factors: random environmental effects, shared environmental effects, and additive and dominant genetic effects. Reproduced and modified from [12] with permission from the publisher.
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Figure
Sub Component: 
Normal
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F6
Highwire: Type: 
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HighWire: Journal/Corpus Code: 
ersbk
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ersbk;9781849840514/1/chapter_4/F6
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ersbk;9781849840514/1/chapter_4/F6
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/ersbk/9781849840514/9781849840514/SEC4/SEC8/F6.atom
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Highwire: cpathalias: 
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Highwire: Variants: 
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Highwire: State: 
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Contributors: 
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<atom:contributor xmlns:atom="http://www.w3.org/2005/Atom" xmlns:hwp="http://schema.highwire.org/Journal" xmlns:nlm="http://schema.highwire.org/NLM/Journal" hwp:inherited="yes" nlm:contrib-type="editor"><atom:name>J. Stuart Elborn</atom:name><nlm:name name-style="western" hwp:sortable="Elborn J. Stuart"><nlm:surname>Elborn</nlm:surname><nlm:given-names>J. Stuart</nlm:given-names></nlm:name></atom:contributor>
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