Summary:
F/HN-SIV transduction leads to persistent gene expression in mouse airways. Mice were transduced with F/HN-SIV-Lux (simian immunodeficiency virus pseudotyped with F (fusion) and HN (haemagglutinin-neuraminidase) proteins from the Sendai virus, and carrying the bacterial luciferase (lux) reporter system) (5×108 transduction units per mouse) by nasal sniffing, or received PBS (negative controls). Luciferase expression was visualised using bioluminescence in vivo imaging, 2–22 months after transduction. Colour scale indicates photon emission in ×106 photons·s−1·cm−2. Reproduced and modified from [66] with permission from the publisher.
Type:
Figure
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Normal
Slug:
F31
Highwire: Type:
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Highwire: Parent:
HighWire: Journal/Corpus Code:
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Contributors:
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