European Respiratory Society

Figure 5

Fri, 2021-07-09 16:03 -- admin
Summary: 
The number of acute pulmonary vasodilator responders according to the three criteria in use, in children versus adults with idiopathic (I)/heritable (H) pulmonary arterial hypertension (PAH); IPAH/HPAH versus PAH associated with congenital heart diseases (CHD); and patients without versus patients with post-tricuspid shunt, respectively. Figures in bars represent absolute numbers of patients. There were 14 (Barst criteria; 20%), 20 (Rich criteria; 29%) and eight (Sitbon criteria; 11%) acute responders in the IPAH/HPAH group, whereas there was one responder (11%) in the CHD group. The criteria used were as follows. Barst criteria [43]: decrease in mean pulmonary artery pressure (Ppa) of ≥20%, unchanged or increased cardiac index, and decreased or unchanged pulmonary-to-systemic vascular resistance ratio. Rich criteria, 1992 [44]: decrease in Ppa and pulmonary to systemic vascular resistance of ≥20%. Sitbon criteria, 2005 [45]: decrease in Ppa of ≥10 mmHg reaching a Ppa value of ≤40 mmHg and an increased or unchanged cardiac output. Reproduced and modified from [42], with permission from the publisher.
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Normal
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F21
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