European Respiratory Society

Figure 5

Fri, 2021-07-09 16:03 -- admin
Summary: 
Negative predictive value (post-test probability of unsuccessful outcome) for respiratory frequency/tidal volume ratio (fR/VT) plotted against the pre-test probability of weaning success. The study number refers to the study as cited in Tobin and Jubran [9]. Of note is study 11, which has a negative predictive value of 0.00 and specificity of 0.00. These values suggest that fR/VT is an unreliable test (and this will also be the natural conclusion reached by a meta-analysis of likelihood ratio). Instead, a negative predictive value of 0.00 and specificity of 0.00 are the values predicted for the pre-test probability of weaning success of 98.2% reported in study 11. •: studies included in the American College of Chest Physicians (ACCP) Task Force's meta-analysis; ○: studies undertaken after publication of the ACCP Task Force's report; –––: curve based on the sensitivity and specificity originally reported by Yang and Tobin [5] and Bayes' formula for 0.01 unit increments in pre-test probability between 0.00 and 1.00; ···········: upper and lower 95% confidence intervals for the predicted relationship of the negative predictive values against pre-test probability. Reproduced from [9] with permission from the publisher.
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