Jean-Luc Vachiéry
- Challenges in the diagnosis and treatment of pulmonary arterial hypertensionBy Jean-Luc Vachiéry and Sean GaineJean-Luc Vachiéry*Pulmonary Vascular Diseases and Heart Failure Clinic, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. #National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.Sean Gaine*Pulmonary Vascular Diseases and Heart Failure Clinic, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. #National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.
- Echocardiography of pulmonary vascular function in asymptomatic carriers of BMPR2 mutationsBy Adriana Pavelescu, Rebecca Vanderpool, Jean-Luc Vachiéry, Ekkehard Grunig and Robert NaeijeAdriana Pavelescu*Dept of Pathophysiology, Faculty of Medicine, Université Libre de BruxellesRebecca Vanderpool*Dept of Pathophysiology, Faculty of Medicine, Université Libre de BruxellesJean-Luc Vachiéry#Pulmonary Hypertension Clinic, Dept of Cardiology, Erasme University Hospital, Brussels, BelgiumEkkehard Grunig¶Center for Pulmonary Hypertension, Thoracic Clinic, University of Heidelberg, Heidelberg, GermanyRobert Naeije*Dept of Pathophysiology, Faculty of Medicine, Université Libre de Bruxelles#Pulmonary Hypertension Clinic, Dept of Cardiology, Erasme University Hospital, Brussels, Belgium
- Exercise testing to predict outcome in idiopathic versus associated pulmonary arterial hypertensionBy Gaël Deboeck, Cristina Scoditti, Sandrine Huez, Jean-Luc Vachiéry, Michel Lamotte, Linda Sharples, Christian Melot and Robert NaeijeGaël Deboeck*Dept of Cardiology, CUB Erasmus University Hospital, Free University of BrusselsCristina Scoditti#University of Bari, Dept of Lung Disease, Bari, ItalySandrine Huez*Dept of Cardiology, CUB Erasmus University Hospital, Free University of BrusselsJean-Luc Vachiéry*Dept of Cardiology, CUB Erasmus University Hospital, Free University of BrusselsMichel Lamotte*Dept of Cardiology, CUB Erasmus University Hospital, Free University of BrusselsLinda Sharples¶Papworth Hospital, Papworth, Cambridge, UKChristian Melot+Dept of Emergency Medicine, Erasmus University Hospital, Free University of BrusselsRobert Naeije§Dept of Physiology, Faculty of Medicine of the Free University of Brussels, Brussels, Belgium
- The transpulmonary pressure gradient for the diagnosis of pulmonary vascular diseaseBy Robert Naeije, Jean-Luc Vachiery, Patrick Yerly and Rebecca VanderpoolRobert Naeije*Dept of Physiology, Faculty of Medicine, Free University BrusselsJean-Luc Vachiery#Dept of Cardiology, Erasme University Hospital, Free University Brussels, Brussels, BelgiumPatrick Yerly#Dept of Cardiology, Erasme University Hospital, Free University Brussels, Brussels, BelgiumRebecca Vanderpool*Dept of Physiology, Faculty of Medicine, Free University Brussels
- Sildenafil (SIL) reduces serum creatinine (SCr) in patients with pulmonary arterial hypertension (PAH): Relationship to clinical outcomesBy David Webb, Jean-Luc Vachiery, Lie-Ju Hwang, Stephen Watt and Julie MaureyDavid Webb1Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United KingdomJean-Luc Vachiery2Departement de Cardiologie, CUB-Hôpital Erasme, Brussels, BelgiumLie-Ju Hwang3Department of Statistics, Specialty Care, Pfizer Inc, New York, NY, United StatesStephen Watt4Medical, Pulmonary Vascular Disease, Pfizer Inc, New York, NY, United StatesJulie Maurey5Regional Medical & Research, Specialty Care - Pulmonary Vascular Disease, Pfizer Inc, New York, NY, United States
- Endothelin-1 downregulates BMP signaling in pulmonary artery smooth muscle cellsBy Hidekazu Maruyama, Celine Dewachter, Asmae Belhaj, Benoit Rondelet, Myriam Remmelink, Jean-Luc Vachiery, Robert Naeije and Laurence DewachterHidekazu Maruyama1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, BelgiumCeline Dewachter1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, BelgiumAsmae Belhaj1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, BelgiumBenoit Rondelet1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, BelgiumMyriam Remmelink2Service d'Anatomie Pathologique, CUB-ULB Hopital Erasme, Brussels, BelgiumJean-Luc Vachiery3Pulmonary Vascular Diseases Clinic, CUB-ULB Hopital Erasme, Brussels, BelgiumRobert Naeije1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, BelgiumLaurence Dewachter1Physiopathology Laboratory, Universite Libre de Bruxelles, Brussels, Belgium
- Insulin-like growth factor-1 contributes to the pulmonary artery smooth muscle cell proliferation in pulmonary arterial hypertensionBy Laurence Dewachter, Céline Dewachter, Asmae Belhaj, Sophie Lalande, Benoit Rondelet, Myriam Remmelink, Jean-Luc Vachiéry and Robert NaeijeLaurence Dewachter1Physiology and Physiopathology, Faculty of Medicine, Université Libre de Bruxelles, Brussels, BelgiumCéline Dewachter1Physiology and Physiopathology, Faculty of Medicine, Université Libre de Bruxelles, Brussels, BelgiumAsmae Belhaj2Cardiovascular and Thoracic Surgery, Mont-Godinne University Hospital, Dinant, BelgiumSophie Lalande1Physiology and Physiopathology, Faculty of Medicine, Université Libre de Bruxelles, Brussels, BelgiumBenoit Rondelet1Physiology and Physiopathology, Faculty of Medicine, Université Libre de Bruxelles, Brussels, BelgiumMyriam Remmelink3Anatomopathology, Erasme Academic Hospital, Brussels, BelgiumJean-Luc Vachiéry4Cardiology, Erasme Academic Hospital, Brussels, BelgiumRobert Naeije1Physiology and Physiopathology, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium
- Navigating the uncharted waters of combination therapy in pulmonary arterial hypertension: COMPASS or dead-reckoningBy Jean-Luc Vachiery and Lewis J. RubinJean-Luc Vachiery1Pulmonary Vascular Diseases Clinic, Dept of Cardiology, Cliniques Universitaires de Bruxelles – Hôpital Erasme, Brussels, BelgiumLewis J. Rubin2Division of Pulmonary and Critical Care Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), Intern…By Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori and Marius HoeperArticle | Published in 2015 in European Respiratory JournalNazzareno Galiè1Representing the European Society of CardiologyRoles: (ESC Chairperson)Marc Humbert2Representing the European Respiratory SocietyRoles: (ERS Chairperson)Jean-Luc Vachiery3Representing the International Society for Heart and Lung TransplantationSimon Gibbs1Representing the European Society of CardiologyIrene Lang1Representing the European Society of CardiologyAdam Torbicki1Representing the European Society of CardiologyGérald Simonneau2Representing the European Respiratory SocietyAndrew Peacock2Representing the European Respiratory SocietyAnton Vonk Noordegraaf2Representing the European Respiratory SocietyMaurice Beghetti4Representing the Association for European Paediatric and Congenital CardiologyArdeschir Ghofrani2Representing the European Respiratory SocietyMiguel Angel Gomez Sanchez1Representing the European Society of CardiologyGeorg Hansmann4Representing the Association for European Paediatric and Congenital CardiologyWalter Klepetko3Representing the International Society for Heart and Lung TransplantationPatrizio Lancellotti1Representing the European Society of CardiologyMarco Matucci5Representing the European League Against RheumatismTheresa McDonagh1Representing the European Society of CardiologyLuc A. Pierard1Representing the European Society of CardiologyPedro T. Trindade1Representing the European Society of CardiologyMaurizio Zompatori6Representing the European Society of Radiology. A full list of collaborators and document reviewers can be found in the AppendixMarius Hoeper2Representing the European Respiratory Society
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), Intern…By Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori and Marius HoeperArticle | Published in 2015 in European Respiratory JournalNazzareno Galiè1Representing the European Society of CardiologyRoles: (ESC Chairperson)Marc Humbert2Representing the European Respiratory SocietyRoles: (ERS Chairperson)Jean-Luc Vachiery3Representing the International Society for Heart and Lung TransplantationSimon Gibbs1Representing the European Society of CardiologyIrene Lang1Representing the European Society of CardiologyAdam Torbicki1Representing the European Society of CardiologyGérald Simonneau2Representing the European Respiratory SocietyAndrew Peacock2Representing the European Respiratory SocietyAnton Vonk Noordegraaf2Representing the European Respiratory SocietyMaurice Beghetti4Representing the Association for European Paediatric and Congenital CardiologyArdeschir Ghofrani2Representing the European Respiratory SocietyMiguel Angel Gomez Sanchez1Representing the European Society of CardiologyGeorg Hansmann4Representing the Association for European Paediatric and Congenital CardiologyWalter Klepetko3Representing the International Society for Heart and Lung TransplantationPatrizio Lancellotti1Representing the European Society of CardiologyMarco Matucci5Representing the European League Against RheumatismTheresa McDonagh1Representing the European Society of CardiologyLuc A. Pierard1Representing the European Society of CardiologyPedro T. Trindade1Representing the European Society of CardiologyMaurizio Zompatori6Representing the European Society of Radiology. A full list of collaborators and document reviewers can be found in the AppendixMarius Hoeper2Representing the European Respiratory Society
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), Intern…By Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori and Marius HoeperArticle | Published in 2015 in European Respiratory JournalNazzareno Galiè1Representing the European Society of CardiologyRoles: (ESC Chairperson)Marc Humbert2Representing the European Respiratory SocietyRoles: (ERS Chairperson)Jean-Luc Vachiery3Representing the International Society for Heart and Lung TransplantationSimon Gibbs1Representing the European Society of CardiologyIrene Lang1Representing the European Society of CardiologyAdam Torbicki1Representing the European Society of CardiologyGérald Simonneau2Representing the European Respiratory SocietyAndrew Peacock2Representing the European Respiratory SocietyAnton Vonk Noordegraaf2Representing the European Respiratory SocietyMaurice Beghetti4Representing the Association for European Paediatric and Congenital CardiologyArdeschir Ghofrani2Representing the European Respiratory SocietyMiguel Angel Gomez Sanchez1Representing the European Society of CardiologyGeorg Hansmann4Representing the Association for European Paediatric and Congenital CardiologyWalter Klepetko3Representing the International Society for Heart and Lung TransplantationPatrizio Lancellotti1Representing the European Society of CardiologyMarco Matucci5Representing the European League Against RheumatismTheresa McDonagh1Representing the European Society of CardiologyLuc A. Pierard1Representing the European Society of CardiologyPedro T. Trindade1Representing the European Society of CardiologyMaurizio Zompatori6Representing the European Society of Radiology. A full list of collaborators and document reviewers can be found in the AppendixMarius Hoeper2Representing the European Respiratory Society
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), Intern…By Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori and Marius HoeperNazzareno Galiè1Representing the European Society of CardiologyRoles: (ESC Chairperson)Marc Humbert2Representing the European Respiratory SocietyRoles: (ERS Chairperson)Jean-Luc Vachiery3Representing the International Society for Heart and Lung TransplantationSimon Gibbs1Representing the European Society of CardiologyIrene Lang1Representing the European Society of CardiologyAdam Torbicki1Representing the European Society of CardiologyGérald Simonneau2Representing the European Respiratory SocietyAndrew Peacock2Representing the European Respiratory SocietyAnton Vonk Noordegraaf2Representing the European Respiratory SocietyMaurice Beghetti4Representing the Association for European Paediatric and Congenital CardiologyArdeschir Ghofrani2Representing the European Respiratory SocietyMiguel Angel Gomez Sanchez1Representing the European Society of CardiologyGeorg Hansmann4Representing the Association for European Paediatric and Congenital CardiologyWalter Klepetko3Representing the International Society for Heart and Lung TransplantationPatrizio Lancellotti1Representing the European Society of CardiologyMarco Matucci5Representing the European League Against RheumatismTheresa McDonagh1Representing the European Society of CardiologyLuc A. Pierard1Representing the European Society of CardiologyPedro T. Trindade1Representing the European Society of CardiologyMaurizio Zompatori6Representing the European Society of Radiology. A full list of collaborators and document reviewers can be found in the AppendixMarius Hoeper2Representing the European Respiratory Society
- Initial combination therapy with ambrisentan (AMB) and tadalafil (TAD) in treatment naïve patients with pulmonary arterial hypertension (PAH): Efficacy and safety in the AMBITION study intent to treat (ITT) populationBy Marius Hoeper, Nazzareno Galie, Joan Albert Barbera, Adaani Frost, Ardeschir Ghofrani, Valerie McLaughlin, Andrew Peacock, Gerald Simonneau, Jean-Luc Vachiery, Christiana Blair, Hunter Gillies, Julia Harris, Jon Langley and Lewis RubinMarius Hoeper1Department of Respiratory Medicine, Hannover Medical School, Hannover, GermanyNazzareno Galie2Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, ItalyJoan Albert Barbera3Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, SpainAdaani Frost4Department of Medicine, Baylor College of Medicine, Houston, United StatesArdeschir Ghofrani5University of Giessen and Marburg Lung Centre (UGMLC), University of Giessen, Giessen, GermanyValerie McLaughlin6Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, United StatesAndrew Peacock7Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United KingdomGerald Simonneau8National Reference Center for Severe Pulmonary Hypertension, Hopital de Bicetre, University of Paris, Paris, FranceJean-Luc Vachiery9Departement de Cardiologie, Hopital Erasme, Brussels, BelgiumChristiana Blair10Department of Biometrics, Gilead Sciences Inc., Foster City, United StatesHunter Gillies11Department of Clinical Research, Gilead Sciences Inc., Foster City, United StatesJulia Harris12Department of Research and Development, GlaxoSmithKline, London, United KingdomJon Langley12Department of Research and Development, GlaxoSmithKline, London, United KingdomLewis Rubin13Department of Medicine, University of California at San Diego, La Jolla, United States
- Endothelin-1 contributes to the downregulation of BMP/BMPR2 signaling induced by hypoxiaBy Hidekazu Maruyama, Céline Dewachter, Asmae Belhaj, Benoit Rondelet, Myriam Remmelink, Jean-Luc Vachiéry, Robert Naeije and Laurence DewachterHidekazu Maruyama1Physiology and Pharmacology, ULB, Brussels, BelgiumCéline Dewachter1Physiology and Pharmacology, ULB, Brussels, BelgiumAsmae Belhaj2Anatomopathology, Erasme Academic Hospital, Brussels, BelgiumBenoit Rondelet2Anatomopathology, Erasme Academic Hospital, Brussels, BelgiumMyriam Remmelink3Cardiology, Erasme Academic Hospital, Brussels, BelgiumJean-Luc Vachiéry1Physiology and Pharmacology, ULB, Brussels, BelgiumRobert Naeije1Physiology and Pharmacology, ULB, Brussels, BelgiumLaurence Dewachter1Physiology and Pharmacology, ULB, Brussels, Belgium
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