Brian O'Connor
- Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459By Dave Singh, Paul Cadden, Michael Hunter, Lisa Pearce Collins, Mike Perkins, Roy Pettipher, Elizabeth Townsend, Shân Vinall and Brian O'ConnorDave Singh*University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundation Trust, WythenshawePaul Cadden*University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundation Trust, WythenshaweMichael Hunter#Oxagen Ltd, AbingdonLisa Pearce Collins#Oxagen Ltd, AbingdonMike Perkins#Oxagen Ltd, AbingdonRoy Pettipher#Oxagen Ltd, AbingdonElizabeth Townsend#Oxagen Ltd, AbingdonShân Vinall#Oxagen Ltd, AbingdonBrian O'Connor¶Dept of Asthma, Allergy and Respiratory Science, Guy's, King's and St Thomas' School of Medicine at King's College Hospital+Respiratory Clinical Trials, London, UK
- The effect of GSK2190915, a 5-lipoxygenase activating protein inhibitor, on the allergen induced asthmatic responseBy Virginia Norris, Jane Bentley, Sandra Kent, Malcolm Boyce, Zuzana Diamant, Dave Singh and Brian O'ConnorVirginia Norris1Drug Discovery, GlaxoSmithKline, Stevenage, United KingdomJane Bentley1Drug Discovery, GlaxoSmithKline, Stevenage, United KingdomSandra Kent1Drug Discovery, GlaxoSmithKline, Stevenage, United KingdomMalcolm Boyce2Clinical Pharmacolgy, Hammersmith Medicines Research, London, United KingdomZuzana Diamant3Clinial Pharmacology, Centre for Human Drug Research, Leiden, NetherlandsDave Singh4Respiratory Medicine, Medicine Evaluation Unit, Manchester, United KingdomBrian O'Connor5Respiratory Medicine, Respiratory Clinical Trials, London, United Kingdom
- The role of MKK3 in allergic and non-allergic inflammatory responses in the lungBy Tatjana Holand, Yanira Riffo-Vasquez, Domenico Spina, Brian O'Connor, Francis Woisin, Mike Marber, Kevin Bacon and Christian RolffTatjana Holand1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomYanira Riffo-Vasquez1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomDomenico Spina1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomBrian O'Connor1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomFrancis Woisin1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomMike Marber2Cardiovascular Research Division, King's College London, London, United KingdomKevin Bacon
- MKK3 is expressed in cells from patients with allergic asthmaBy Tatjana Holand, Yanira Riffo-Vasquez, Domenico Spina, Brian O'Connor, Francis Woisin, Mike Barber, Kevin Bacon, Christian Rohlff and Clive PageTatjana Holand1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomYanira Riffo-Vasquez1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomDomenico Spina1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomBrian O'Connor1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomFrancis Woisin1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United KingdomMike Barber2Cardiovascular Research Division, King's College London, London, United KingdomKevin BaconChristian RohlffClive Page1Sackler Institute of Pulmonary Pharmacology, King's College London, London, United Kingdom
- Effects of the novel toll-like receptor 7 (TLR7) agonist AZD8848 on allergen-induced responses in patients with mild asthmaBy Brian Leaker, Dave Singh, Sam Lindgren, Gun Almqvist, Barbara Young and Brian O'ConnorBrian Leaker1RCT, Respiratory Clinical Trials Ltd, London, United KingdomDave Singh2Medicines Evaluation Unit Ltd, University of Manchester, United KingdomSam Lindgren3Research and Development, AstraZeneca, Mölndal, SwedenGun Almqvist3Research and Development, AstraZeneca, Mölndal, SwedenBarbara Young4Research and Development, AstraZeneca, Charnwood, Loughborugh, United KingdomBrian O'Connor1RCT, Respiratory Clinical Trials Ltd, London, United Kingdom
- The effect of the novel SHIP1 activator AQX-1125 on allergen-induced responses in mild to moderate asthmaBy Brian Leaker, Brian O'Connor, Peter Barnes, Lloyd Mckenzie, David Chernoff, Judith Neville, Pat Tam, Grant Stenton, Curtis Harwig and Tom MacRuryBrian Leaker1Respiratory Clinical Trials Ltd, 18-22 Queen Anne St, London, United KingdomBrian O'Connor1Respiratory Clinical Trials Ltd, 18-22 Queen Anne St, London, United KingdomPeter Barnes2Thoracic Medicine, National Heart and Lung Institute, London, United KingdomLloyd Mckenzie3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaDavid Chernoff3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaJudith Neville3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaPat Tam3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaGrant Stenton3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaCurtis Harwig3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, CanadaTom MacRury3Aquinox Pharmaceuticals Inc, Aqunionx Pharmaceuticals Inc, Vancouver, Canada
- Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459By Dave Singh, Paul Cadden, Michael Hunter, Lisa Pearce Collins, Mike Perkins, Roy Pettipher, Elizabeth Townsend, Shân Vinall and Brian O'ConnorArticle | Published in 2012 in European Respiratory JournalDave SinghPaul CaddenMichael HunterLisa Pearce CollinsMike PerkinsRoy PettipherElizabeth TownsendShân Vinall
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