Paul O'Byrne
- Late-breaking abstract: Changes in cortisol levels in the plasma of asthmatic individuals undergoing allergen inhalation challenge differentiate isolated early from dual respondersBy Scott Tebbutt, Sarah Kam, Amrit Singh, Louis-Philippe Boulet, Mark FitzGerald, Gail Gauvreau and Paul O'ByrneScott Tebbutt1The James Hogg Research Centre, University of British Columbia, Vancouver, BC, CanadaSarah Kam1The James Hogg Research Centre, University of British Columbia, Vancouver, BC, CanadaAmrit Singh1The James Hogg Research Centre, University of British Columbia, Vancouver, BC, CanadaLouis-Philippe Boulet2Centre de Pneumologie de l'Hopital Laval, Universite Laval, Sainte-Foy, QC, CanadaMark FitzGerald3Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, BC, CanadaGail Gauvreau4Department of Medicine, McMaster University, Hamilton, ON, CanadaPaul O'Byrne4Department of Medicine, McMaster University, Hamilton, ON, Canada
- Inhaled budesonide induces corticosteroid-dependent gene expression in asthmatics: Validation in primary epithelial and airways smooth muscle cellsBy Robert Newton, Elizabeth King, Christopher Rider, Carol Gwozd, Neil Holden, Jane Eddlestone, Bruce Zuraw, Richard Leigh, Paul O'Byrne and Margaret KellyRobert Newton1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaElizabeth King1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaChristopher Rider1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaCarol Gwozd1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaNeil Holden1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaJane Eddlestone2San Diego School of Medicine, University of California, La Jolla, CA, United StatesBruce Zuraw2San Diego School of Medicine, University of California, La Jolla, CA, United StatesRichard Leigh1Airways Inflammation Research Group, University of Calgary, Calgary, AB, CanadaPaul O'Byrne3Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, CanadaMargaret Kelly1Airways Inflammation Research Group, University of Calgary, Calgary, AB, Canada
- Fluticasone propionate inhaled 3 hours after an early allergic reaction partially inhibits the late phase reactionBy Bart Jacobs, Gail Gauvreau, Rick Watson, Abbey Torek, Karen Howie, Kieran Killian and Paul O'ByrneBart Jacobs1Pharmacy, Utrecht University, Utrecht, NetherlandsGail Gauvreau2Medicine, McMaster University, Hamilton, ON, CanadaRick Watson2Medicine, McMaster University, Hamilton, ON, CanadaAbbey Torek2Medicine, McMaster University, Hamilton, ON, CanadaKaren Howie2Medicine, McMaster University, Hamilton, ON, CanadaKieran Killian2Medicine, McMaster University, Hamilton, ON, CanadaPaul O'Byrne2Medicine, McMaster University, Hamilton, ON, Canada
- Risks of diabetes mellitus and hyperglycaemic adverse events in patients with COPD taking inhaled corticosteroidsBy Stephen Rennard, Paul O'Byrne, Finn Radner, Stefan Peterson, Ella Ekholm, Bengt Lindberg and Don SinStephen Rennard1Internal Medicine Section of Pulmonary and Critical Care, University of Nebraska Medical Center, Omaha, United StatesPaul O'Byrne2Faculty of Health Sciences, Michael G DeGroote School of Medicine, Hamilton, CanadaFinn Radner3Department of Clinical Sciences, AstraZeneca Research and Development, Lund, SwedenStefan Peterson3Department of Clinical Sciences, AstraZeneca Research and Development, Lund, SwedenElla Ekholm3Department of Clinical Sciences, AstraZeneca Research and Development, Lund, SwedenBengt Lindberg3Department of Clinical Sciences, AstraZeneca Research and Development, Lund, SwedenDon Sin4Department of Medicine, University of British Columbia, Vancouver, Canada
- Risks of diabetes mellitus and hyperglycaemic adverse events in patients with asthma taking inhaled corticosteroidsBy Paul O'Byrne, Stephen Rennard, Radner Finn, Stefan Peterson, Lars-Goran Carlsson and Don SinPaul O'Byrne1Michael G DeGroote School of Medicine, McMaster University, Hamilton, CanadaStephen Rennard2Internal Medicine Section of Pulmonary and Critical Care, Nebraska Medical Center, NE, United StatesRadner Finn3Clinical Sciences, AstraZeneca R&D, Lund, SwedenStefan Peterson3Clinical Sciences, AstraZeneca R&D, Lund, SwedenLars-Goran Carlsson3Clinical Sciences, AstraZeneca R&D, Lund, SwedenDon Sin4Department of Medicine, University of British Columbia, Vancouver, Canada
- Effects of anti-M1 prime monoclonal antibody, MEMP1972A following allergen challenge in patients with mild asthmaBy Gail Gauvreau, Louis-Philippe Boulet, Donald Cockcroft, Beth Davis, Mark Fitzgerald, Richard Leigh, Barbro Dahlen, Irvin Mayers, Heleen Scheerens, Romeo Maciuca, John Matthews, Jeffrey Harris and Paul O'ByrneGail Gauvreau1Department of Medicine, McMaster University, Ontario, CanadaLouis-Philippe Boulet2Department of Pneumology, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Hôpital Laval, Quebec, CanadaDonald Cockcroft3Department of Medicine, University of Saskatchewan, Saskatoon, CanadaBeth Davis3Department of Medicine, University of Saskatchewan, Saskatoon, CanadaMark Fitzgerald4Department of Medicine, University of British Columbia, Vancouver, BC, CanadaRichard Leigh5Department of Medicine, University of Calgary, AB, CanadaBarbro Dahlen6Department of Medicine, Karolinska Institute, Stockholm, SwedenIrvin Mayers7Department of Medicine, University of Alberta, AB, CanadaHeleen Scheerens8PD Biomarkers, Genentech, Inc, South San Francisco, United StatesRomeo Maciuca9Biostatistics, Genetech, Inc, South San Francisco, United StatesJohn Matthews10Product Development - Immunology, Genentech, Inc, South San Francisco, United StatesJeffrey Harris11Research and Early Development, Genentech, Inc, South San Francisco, United StatesPaul O'Byrne1Department of Medicine, McMaster University, Ontario, Canada
- Efficacy and safety of once-daily (OD) fluticasone furoate (FF) in patients with persistent asthma: A 24-week randomised trialBy Jan Lötvall, Eugene Bleecker, William Busse, Paul O'Byrne, Ashley Woodcock, Eric Bateman, Edward Kerwin, Sally Stone, Richard Forth and Loretta JacquesJan Lötvall1Krefting Research Centre, University of Gothenburg, SwedenEugene Bleecker2Center for Genomics and Personalized Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, United StatesWilliam Busse3Department of Medicine, University of Wisconsin, Madison, WI, United StatesPaul O'Byrne4Department of Medicine, Michael G DeGroote School of Medicine, Hamilton, ON, CanadaAshley Woodcock5School of Translational Medicine, University of Manchester, United KingdomEric Bateman6Department of Medicine, University of Cape Town, South AfricaEdward Kerwin7Allergy & Asthma Center, Clinical Research Institute of Southern Oregon, Medford, OR, United StatesSally Stone8Respiratory Medicine Development Centre, GlaxoSmithKline, Uxbridge, United StatesRichard Forth9Quantitative Sciences Division, GlaxoSmithKline, Research Triangle Park, Durham, NC, United StatesLoretta Jacques8Respiratory Medicine Development Centre, GlaxoSmithKline, Uxbridge, United States
- Magnitude of the late allergen response in seasonal vs perennial allergen bronchoprovocationBy Marie-Eve Boulay, Gail Gauvreau, Paul O'Byrne and Louis-Philippe BouletMarie-Eve Boulay1Research Center, IUCPQ, Quebec, QC, CanadaGail Gauvreau2Department of Medicine, McMaster University, Hamilton, ON, CanadaPaul O'Byrne2Department of Medicine, McMaster University, Hamilton, ON, CanadaLouis-Philippe Boulet1Research Center, IUCPQ, Quebec, QC, Canada
- Blockade of TSLP pathway alters asthma biomarkersBy Jeannette Bigler, Michael Boedigheimer, Kevin Gorski, Paul O'Byrne, Ying Wang, Gail Gauvreau, Louis-Philippe Boulet, Donald Cockcroft, Mark FitzGerald, Beth Davis, Clapton Dias, Lynn Smith, Edgar Bautista, Richard Leigh, Andrew Welcher and Jane ParnesJeannette Bigler1Medical Sciences, Amgen Inc, Seattle, WA,Michael Boedigheimer2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Kevin Gorski2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Paul O'Byrne3Devision of Respirology, Department of Medicine, McMaster University, Hamilton, CanadaYing Wang2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Gail Gauvreau3Devision of Respirology, Department of Medicine, McMaster University, Hamilton, CanadaLouis-Philippe Boulet4Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Laval, CanadaDonald Cockcroft5Division of Respirology, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, CanadaMark FitzGerald6Division of Respiratory Medicine, University of British Columbia, Vancouver, CanadaBeth Davis5Division of Respirology, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, CanadaClapton Dias2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Lynn Smith2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Edgar Bautista2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Richard Leigh7Snyder Institute for Chronic Diseases, University of Calgary, Calgary, CanadaAndrew Welcher2Medical Sciences, Amgen Inc, Thousand Oaks, CA,Jane Parnes2Medical Sciences, Amgen Inc, Thousand Oaks, CA,
- Late-breaking abstract: Effects of a dual CysLT1/2 antagonist, ONO-6950, on allergen-induced airway responses in subjects with mild allergic asthmaBy Gail Gauvreau, Louis-Philippe Boulet, J. Mark FitzGerald, Donald Cockcroft, Beth Davis, Richard Leigh, Masaya Tanaka, John Fourre, Makoto Tanaka, Toshiya Nabata and Paul O'ByrneGail Gauvreau1Medicine, McMaster University, Hamilton, CanadaLouis-Philippe Boulet2Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, CanadaJ. Mark FitzGerald3Medicine, University of British Columbia, Vancouver, CanadaDonald Cockcroft4Medicine, University of Saskatchewan, Saskatoon, CanadaBeth Davis4Medicine, University of Saskatchewan, Saskatoon, CanadaRichard Leigh5Medicine, University of Calgary, Calgary, CanadaMasaya Tanaka6Translational Medicine Center, ONO Pharmaceutical Co., Ltd., Osaka, JapanJohn Fourre6Translational Medicine Center, ONO Pharmaceutical Co., Ltd., Osaka, JapanMakoto Tanaka6Translational Medicine Center, ONO Pharmaceutical Co., Ltd., Osaka, JapanToshiya Nabata6Translational Medicine Center, ONO Pharmaceutical Co., Ltd., Osaka, JapanPaul O'Byrne1Medicine, McMaster University, Hamilton, Canada
- LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimersBy Kevin Bacon, Emma Moss, Karen Bingham, Louis-Philippe Boulet, Mark Fitzgerald, Gail Gauvreau, Paul O'Byrne, Taylor Gilliland, Tracy Handel, Tai-Wei Ly and Stefen BoehmeKevin Bacon1Biology, Axikin Pharmaceuticals, Inc, San Diego, CA United StatesEmma Moss2Biology, Biopta Ltd., Glasgow, United KingdomKaren Bingham2Biology, Biopta Ltd., Glasgow, United KingdomLouis-Philippe Boulet3IUCPQ, Institut de Cardiologie et de Pneumologie de l'Hôpital Laval, IUCPQ, Institut de Cardiologie et de Pneumologie de l'Hopital Laval, Quebec, CanadaMark Fitzgerald4UBC Respiratory Division, University of British Columbia, Vancouver, CanadaGail Gauvreau5Department of Medicine, McMaster University, Hsmilton, CanadaPaul O'Byrne5Department of Medicine, McMaster University, Hsmilton, CanadaTaylor Gilliland6Dept of Pharmacology, School of Medicine, University of California, San Diego, San Diego, United StatesTracy Handel6Dept of Pharmacology, School of Medicine, University of California, San Diego, San Diego, United StatesTai-Wei Ly1Biology, Axikin Pharmaceuticals, Inc, San Diego, CA United StatesStefen Boehme1Biology, Axikin Pharmaceuticals, Inc, San Diego, CA United States
- The dynamic change of IL-25 and its receptor expression during allergen challenge in asthmatic subjectsBy Wei Tang, Steven Smith, Paul O'Byrne and Roma SehmiWei Tang1Depatment of Respiratory Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China2Asthma Research Group, Department of Medicine, McMaster University, Hamilton, CanadaSteven Smith2Asthma Research Group, Department of Medicine, McMaster University, Hamilton, Canada3Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, CanadaPaul O'Byrne2Asthma Research Group, Department of Medicine, McMaster University, Hamilton, Canada3Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, CanadaRoma Sehmi2Asthma Research Group, Department of Medicine, McMaster University, Hamilton, Canada3Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, Canada
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About the ERS books
The ERS Monograph is the quarterly book series from the European Respiratory Society. Each Monograph covers a specific area of respiratory medicine, providing in-depth reviews that give clinicians at all levels a concise, comprehensive guide to symptoms, diagnosis and treatment.
The ERS Handbooks are compact guides to broad areas of the respiratory field. Launched in 2010, the series now covers adult, paediatric and sleep respiratory medicine, and a companion volume of self-assessment questions is available. In 2015, the first ERS Practical Handbook, on Noninvasive Ventilation, was added to the series
