Martijn C. Nawijn
- Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in miceBy Loes E.M. Kistemaker, I.S.T. Bos, Machteld N. Hylkema, Martijn C. Nawijn, Pieter S. Hiemstra, Jürgen Wess, Herman Meurs, Huib A.M. Kerstjens and Reinoud GosensLoes E.M. Kistemaker1Dept of Molecular Pharmacology, University of Groningen, Groningen2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, GroningenI.S.T. Bos1Dept of Molecular Pharmacology, University of Groningen, Groningen2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, GroningenMachteld N. Hylkema2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, Groningen3Dept of Pathology and Medical Biology, University Medical Centre Groningen, GroningenMartijn C. Nawijn2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, Groningen3Dept of Pathology and Medical Biology, University Medical Centre Groningen, GroningenPieter S. Hiemstra4Dept of Pulmonology, Leiden University Medical Centre, LeidenJürgen Wess5Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USAHerman Meurs1Dept of Molecular Pharmacology, University of Groningen, Groningen2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, GroningenHuib A.M. Kerstjens2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, Groningen6Dept of Respiratory Medicine, University Medical Centre Groningen, Groningen, The NetherlandsReinoud Gosens1Dept of Molecular Pharmacology, University of Groningen, Groningen2GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, Groningen
- A specific DAMP profile identifies susceptibility to smoke-induced airway inflammationBy Simon D. Pouwels, Irene H. Heijink, Antoon J.M. van Oosterhout and Martijn C. NawijnSimon D. Pouwels1Dept of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands3Both authors contributed equallyIrene H. Heijink1Dept of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands3Both authors contributed equallyAntoon J.M. van Oosterhout1Dept of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Both authors contributed equallyMartijn C. Nawijn1Dept of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Both authors contributed equally
- Protocadherin-1: epithelial barrier dysfunction in asthma and eczemaBy Grissel Faura Tellez, Martijn C. Nawijn and Gerard H. KoppelmanGrissel Faura Tellez1University of Groningen, University Medical Center Groningen, Beatrix Children’s Hospital, Dept of Pediatric Pulmonology and Pediatric Allergology, Groningen2University of Groningen, University Medical Center Groningen, Laboratory of Allergology and Pulmonary Diseases, Dept of Pathology and Medical Biology, Groningen3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UKMartijn C. Nawijn2University of Groningen, University Medical Center Groningen, Laboratory of Allergology and Pulmonary Diseases, Dept of Pathology and Medical Biology, Groningen3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsGerard H. Koppelman1University of Groningen, University Medical Center Groningen, Beatrix Children’s Hospital, Dept of Pediatric Pulmonology and Pediatric Allergology, Groningen3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- Late-breaking abstract: Inhibition of Pim1 kinase augments the anti-viral response to rhinovirus infectionBy Maaike de Vries, Nicole Bedke, Natalie P. Smithers, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesMaaike de Vries1Laboratory of Experimental Pulmonology and Inflammation Research, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsNicole Bedke2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, United KingdomNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, United KingdomPeter H. Howarth2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, United KingdomMartijn C. Nawijn1Laboratory of Experimental Pulmonology and Inflammation Research, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, United Kingdom
- Pim1 kinase affects allergic asthma in a HDM-driven mice modelBy Maaike de Vries, Irene H. Heijink, Laura Hesse, Antoon J.M. van Oosterhout and Martijn C. NawijnMaaike de Vries1EXPIRE, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsIrene H. Heijink1EXPIRE, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsLaura Hesse1EXPIRE, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsAntoon J.M. van Oosterhout1EXPIRE, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsMartijn C. Nawijn1EXPIRE, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
- Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patientsBy Simon D. Pouwels, Martijn C. Nawijn, Erik Bathoorn, Annelies Riezebos-Brilman, Antoon J.M. van Oosterhout, Huib A.M. Kerstjens and Irene H. HeijinkArticle | Published in 2015 in European Respiratory JournalSimon D. Pouwels1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsMartijn C. Nawijn1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsErik Bathoorn3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAnnelies Riezebos-Brilman3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAntoon J.M. van Oosterhout1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsHuib A.M. Kerstjens2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsIrene H. Heijink1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cellsBy Maaike de Vries, Natalie P. Smithers, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesArticle | Published in 2015 in European Respiratory JournalMaaike de Vries1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKPeter H. Howarth4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UKMartijn C. Nawijn1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK
- Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patientsBy Simon D. Pouwels, Martijn C. Nawijn, Erik Bathoorn, Annelies Riezebos-Brilman, Antoon J.M. van Oosterhout, Huib A.M. Kerstjens and Irene H. HeijinkArticle | Published in 2015 in European Respiratory JournalSimon D. Pouwels1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsMartijn C. Nawijn1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsErik Bathoorn3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAnnelies Riezebos-Brilman3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAntoon J.M. van Oosterhout1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsHuib A.M. Kerstjens2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsIrene H. Heijink1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cellsBy Maaike de Vries, Natalie P. Smithers, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesArticle | Published in 2015 in European Respiratory JournalMaaike de Vries1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKPeter H. Howarth4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UKMartijn C. Nawijn1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK
- Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patientsBy Simon D. Pouwels, Martijn C. Nawijn, Erik Bathoorn, Annelies Riezebos-Brilman, Antoon J.M. van Oosterhout, Huib A.M. Kerstjens and Irene H. HeijinkSimon D. Pouwels1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsMartijn C. Nawijn1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsErik Bathoorn3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAnnelies Riezebos-Brilman3Dept of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsAntoon J.M. van Oosterhout1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsHuib A.M. Kerstjens2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsIrene H. Heijink1Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cellsBy Maaike de Vries, Natalie P. Smithers, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesMaaike de Vries1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKPeter H. Howarth4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UKMartijn C. Nawijn1Laboratory of Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands3GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK
- Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbationsBy Maaike de Vries, Nicole Bedke, Natalie P. Smithers, Matthew Loxham, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesArticle | Published in 2016 in European Respiratory JournalMaaike de Vries1University of Groningen, University Medical Center Groningen, Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, Groningen, The Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK3University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The NetherlandsNicole Bedke2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKMatthew Loxham2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKPeter H. Howarth2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UKMartijn C. Nawijn1University of Groningen, University Medical Center Groningen, Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, Groningen, The Netherlands3University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK
- Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbationsBy Maaike de Vries, Nicole Bedke, Natalie P. Smithers, Matthew Loxham, Peter H. Howarth, Martijn C. Nawijn and Donna E. DaviesMaaike de Vries1University of Groningen, University Medical Center Groningen, Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, Groningen, The Netherlands2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK3University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The NetherlandsNicole Bedke2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKNatalie P. Smithers2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKMatthew Loxham2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UKPeter H. Howarth2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UKMartijn C. Nawijn1University of Groningen, University Medical Center Groningen, Experimental Pulmonology and Inflammation Research, Dept of Pathology and Medical Biology, Groningen, The Netherlands3University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The NetherlandsDonna E. Davies2Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK4National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK
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