Katsutoshi Nakayama
- Insufficient autophagy is involved in accelerated cellular senescence in the pathophysiology of COPDBy Satoko Fujii, Hiromichi Hara, Jun Araya, Naoki Takasaka, Yoko Yumino, Jun Kojima, Takeo Ishikawa, Takanori Numata, Makoto Kawaishi, Jun Hirano, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYoko Yumino1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakeo Ishikawa1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Hirano2Division of Respiratory Diseases, Department of Surgery, Jikei University School of Medicine, Tokyo, JapanMakoto Odaka2Division of Respiratory Diseases, Department of Surgery, Jikei University School of Medicine, Tokyo, JapanToshiaki Morikawa2Division of Respiratory Diseases, Department of Surgery, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescenceBy Naoki Takasaka, Jun Araya, Hiromichi Hara, Satoko Fujii, Yoko Yumino, Takanori Munata, Makoto Kawaishi, Jun Hirano, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanYoko Yumino1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanTakanori Munata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanJun Hirano2Division of Chest Diseases, Department of Surgery, Jikei University School of Medicine, Minatoku, Tokyo, JapanMakoto Odaka2Division of Chest Diseases, Department of Surgery, Jikei University School of Medicine, Minatoku, Tokyo, JapanToshiaki Morikawa2Division of Chest Diseases, Department of Surgery, Jikei University School of Medicine, Minatoku, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Minatoku, Tokyo, Japan
- The evaluation of systemic inflammation in COPD patients comorbided with cardiovascular diseases or diabetes mellitusBy Yoko Yumino, Satoko Fujii, Naoki Takasaka, Jun Kojima, Hiromichi Hara, Takanori Numata, Takeo Ishikawa, Makoto Kawaishi, Keisuke Saito, Jun Araya, Katsutoshi Nakayama and Kazuyoshi KuwanoYoko YuminoDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSatoko FujiiDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki TakasakaDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun KojimaDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromichi HaraDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori NumataDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakeo IshikawaDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto KawaishiDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKeisuke SaitoDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun ArayaDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKatsutoshi NakayamaDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi KuwanoDivision of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Insulin-dependent PI3-Kinase/Akt and ERK signaling pathways inhibit TLR3-mediated HBEC apoptosisBy Takanori Numata, Jun Araya, Satoko Fujii, Hiromichi Hara, Naoki Takasaka, Yoko Yumino, Makoto Kawaishi, Jun Hirano, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoTakanori Numata1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanJun Araya1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanSatoko Fujii1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanYoko Yumino1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanJun Hirano2Division of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanMakoto Odaka2Division of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanToshiaki Morikawa2Division of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Department of Internal Medicine, Division of Respiratory Diseases, Jikei University School of Medicine, Tokyo, Japan
- Cigarette smoke-induced oxidative modification of creatine kinase B (CKB) is involved in the pathogenesis of COPD in terms of acceleration of bronchial epithelial cell senescenceBy Hiromichi Hara, Jun Araya, Naoki Takasaka, Jun Kojima, Yoko Yumino, Satoko Fujii, Takanori Numata, Makoto Kawaishi, Jun Hirano, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYoko Yumino1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Hirano2Department of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanMakoto Odaka2Department of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanToshiaki Morikawa2Department of Chest Surgery, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Secondary pulmonary alveolar proteinosis associated with IgG4-related diseaseBy Jun Kojima, Hiromichi Hara, Takanori Numata, Kenichiro Shimizu, Makoto Kawaishi, Keisuke Saito, Jun Araya, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoJun Kojima1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanHiromichi Hara1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanTakanori Numata1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanKenichiro Shimizu1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanMakoto Kawaishi1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanKeisuke Saito1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanJun Araya1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanYumi Kaneko1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanKatsutoshi Nakayama1Jikei University School of Medicine, Respiratory Diseases, Tokyo, JapanKazuyoshi Kuwano1Jikei University School of Medicine, Respiratory Diseases, Tokyo, Japan
- SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescenceBy Naoki Takasaka, Jun Araya, Hiromichi Hara, Saburo Ito, Satoko Fujii, Kenichiro Shimizu, Makoto Kawaishi, Takanori Numata, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanToshiaki Morikawa2Division of Chest Diseases, Department of Surgery, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Clinical outcome of S-1 monotherapy in patients with advanced non-small cell lung cancer after treatment of pemetrexedBy Makoto Kawaishi, Hiroshi Wakui, Yutaka Yoshii, Kenji Kobayashi, Saburo Ito, Naoki Takasaka, Jun Kojima, Takeo Ishikawa, Kenichiro Shimizu, Takanori Numata, Hirromichi Hara, Keisuke Saito, Yumi Kaneko, Jun Araya, Katsutoshi Nakayama and Kazuyoshi KuwanoMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiroshi Wakui1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenji Kobayashi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakeo Ishikawa1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHirromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKeisuke Saito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Involvement of mitochondrial fragmentation in cigarette smoke induced-bronchial epithelial cell senescenceBy Hiromichi Hara, Saburo Ito, Jun Araya, Kenji Kobayashi, Hiroshi Wakui, Yutaka Yoshii, Naoki Takasaka, Chikako Tsurushige, Jun Kojima, Kenichiro Shimizu, Takeo Ishikawa, Takanori Numata, Makoto Kawaishi, Keisuke Saito, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenji Kobayashi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiroshi Wakui1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanChikako Tsurushige1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakeo Ishikawa1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKeisuke Saito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- The involvement of thrombospondin-1 in COPD pathogenesis through IL-8 productionBy Takeo Ishikawa, Katsutoshi Nakayama, Jiro Mikami, Saburo Ito, Naoki Takasaka, Yoko Yumino, Satoko Fujii, Chikako Tsurushige, Jun Kojima, Takanori Numata, Hiromichi Hara, Makoto Kawaishi, Jun Araya and Kazuyoshi KuwanoTakeo Ishikawa1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanJiro Mikami1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanYoko Yumino1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanChikako Tsurushige1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
- Etiologies of acute exacerbation of bronchial asthma in adults by real-time polymerase chain reactionBy Kenichiro Shimizu, Yutaka Yoshii, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hiromichi Hara, Takanori Numata, Makoto Kawaishi, Keisuke Saito, Jun Araya, Katsutoshi Nakayama and Kazuyoshi KuwanoKenichiro Shimizu1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanMiyuki Morozumi2Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, JapanNaoko Chiba2Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, JapanKimiko Ubukata2Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, JapanHiromichi Hara1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanKeisuke Saito1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanJun Araya1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Respiratory Medicine, The Jikei University School of Medicine, Tokyo, Japan
- Mitophagic regulation of myofibroblast differentiation in lung fibroblastsBy Kenji Kobayashi, Jun Araya, Hiromichi Hara, Yusuke Kurita, Saburo Ito, Naoki Takasaka, Satoko Fujii, Shunsuke Minagawa, Jun Kojima, Takanori Numata, Kenichiro Shimizu, Makoto Kawaishi, Yumi Kaneko, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi KuwanoKenji Kobayashi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYusuke Kurita1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSatoko Fujii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanShunsuke Minagawa1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanToshiaki Morikawa2Division of Chest Diseases, Department of Surgery, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- PINK1-Parkin pathway-mediated mitophagy is involved in cigarette smoke extract (CSE)-induced cellular senescence in human bronchial epithelial cells (HBEC)By Saburo Ito, Jun Araya, Hiromichi Hara, Yusuke Kurita, Kenji Kobayashi, Naoki Takasaka, Hiroshi Wakui, Yutaka Yoshii, Shunsuke Minagawa, Jun Kojima, Takanori Numata, Kenichiro Shimizu, Makoto Kawaishi, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoSaburo Ito1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYusuke Kurita1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenji Kobayashi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiroshi Wakui1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanShunsuke Minagawa1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Metformin inhibits TGF-b-induced myofibroblast differentiation through AMPK activationBy Naoki Takasaka, Jun Araya, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hiroshi Wakui, Yutaka Yoshii, Shunsuke Minagawa, Jun Kojima, Hiromichi Hara, Takanori Numata, Kenichiro Shimizu, Makoto Kawaishi, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoNaoki Takasaka1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanYusuke Kurita1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKenji Kobayashi1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanHiroshi Wakui1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanShunsuke Minagawa1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, Japan
- Transcription factor EB (TFEB) regulates cigarette smoke extract (CSE)-induced cellular senescenceBy Yusuke Kurita, Jun Araya, Hiromiti Hara, Kenji Kobayashi, Saburo Ito, Naoki Takasaka, Hiroshi Wakui, Yutaka Yoshii, Shunsuke Minagawa, Jun Kojima, Takanori Numata, Kenichiro Shimizu, Makoto Kawaishi, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoYusuke Kurita1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiromiti Hara1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenji Kobayashi1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanSaburo Ito1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanHiroshi Wakui1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanShunsuke Minagawa1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Disease Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
- Multiplex real-time polymerase chain reaction is useful in diagnosing pathogens causing community-acquired pneumonia including atypical bacteria and virusesBy Yutaka Yoshii, Kenichiro Shimizu, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hironori Uruga, Shigeo Hanada, Kazuma Kishi, Hiroshi Wakui, Shunsuke Minagawa, Jun Kojima, Hiromichi Hara, Takanori Numata, Makoto Kawaishi, Jun Araya, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoYutaka Yoshii1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanKenichiro Shimizu1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanMiyuki Morozumi2Department of Infectious Disease, Keio University School of Medicine, Tokyo, JapanNaoko Chiba2Department of Infectious Disease, Keio University School of Medicine, Tokyo, JapanKimiko Ubukata2Department of Infectious Disease, Keio University School of Medicine, Tokyo, JapanHironori Uruga3Department of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Tokyo, JapanShigeo Hanada3Department of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Tokyo, JapanKazuma Kishi3Department of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Tokyo, JapanHiroshi Wakui1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanShunsuke Minagawa1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanJun Kojima1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
- Viral and bacterial etiologies in acute exacerbation of COPD detected using a multiplex real-time polymerase chain reactionBy Kenichiro Shimizu, Yutaka Yoshii, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hironori Uruga, Shigeo Hanada, Saburo Ito, Naoki Takasaka, Hiromichi Hara, Takanori Numata, Makoto Kawaishi, Jun Araya, Yumi Kaneko, Katsutoshi Nakayama and Kazuyoshi KuwanoKenichiro Shimizu1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanYutaka Yoshii1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanMiyuki Morozumi2Department of Infectious Diseases, Keio University, Tokyo, JapanNaoko Chiba2Department of Infectious Diseases, Keio University, Tokyo, JapanKimiko Ubukata2Department of Infectious Diseases, Keio University, Tokyo, JapanHironori Uruga3Department of Respiratory Medicine, Toranomon Hospital, Tokyo, JapanShigeo Hanada3Department of Respiratory Medicine, Toranomon Hospital, Tokyo, JapanSaburo Ito1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanNaoki Takasaka1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanHiromichi Hara1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanTakanori Numata1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanMakoto Kawaishi1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanJun Araya1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanYumi Kaneko1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKatsutoshi Nakayama1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, JapanKazuyoshi Kuwano1Division of Respiratory Diseases, The Jikei University School of Medicine, Tokyo, Japan
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About the ERS books
The ERS Monograph is the quarterly book series from the European Respiratory Society. Each Monograph covers a specific area of respiratory medicine, providing in-depth reviews that give clinicians at all levels a concise, comprehensive guide to symptoms, diagnosis and treatment.
The ERS Handbooks are compact guides to broad areas of the respiratory field. Launched in 2010, the series now covers adult, paediatric and sleep respiratory medicine, includes a companion volume of self-assessment questions and features the ERS Practical Handbooks.
