Jacek Musial
- Collagen receptor α2β1 integrin is overexpressed on CD4 and CD8 peripheral blood T lymphocytes in long-lasting clinically stable asthmaBy Joanna Zuk, Stanislawa Bazan-Socha and Jacek MusialJoanna ZukII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, PolandStanislawa Bazan-SochaII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, PolandJacek MusialII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland
- Inhibition of collagen receptors: α1β1 and α2β1 integrins, has no impact on lymphocytes, but decreases eosinophil transmigration through human extracellular matrix and collagen I coated insertsBy Stanislawa Bazan-Socha, Joanna Zuk, Cezary Marcinkiewicz and Jacek MusialStanislawa Bazan-SochaII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland Department of Biology, College of Science and Technology, Philadelphia, United States II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, PolandJoanna ZukII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland Department of Biology, College of Science and Technology, Philadelphia, United States II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, PolandCezary MarcinkiewiczII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland Department of Biology, College of Science and Technology, Philadelphia, United States II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, PolandJacek MusialII Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland Department of Biology, College of Science and Technology, Philadelphia, United States II Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland
- Inhibition of collagen receptors: α1β1 and α2β1 integrins decreases eosinophil transmigration, but has no impact on peripheral blood mononuclear cell movement through human microvascular endothelial cell lung monolayerBy Stanislawa Bazan-Socha, Joanna Zuk, Cezary Macinkiewicz, Lech Zareba, Hanna Plutecka, Ewa Mlicka-Kowalczyk and Jacek MusialStanislawa Bazan-Socha1Dept. of Internal Medicine, Unit of Allergy and Clinical Immunology, Jagiellonian University Medical College, Krakow, PolandJoanna Zuk1Dept. of Internal Medicine, Unit of Allergy and Clinical Immunology, Jagiellonian University Medical College, Krakow, PolandCezary Macinkiewicz2Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, United StatesLech Zareba3Institute of Mathematics, University of Rzeszow, PolandHanna Plutecka1Dept. of Internal Medicine, Unit of Allergy and Clinical Immunology, Jagiellonian University Medical College, Krakow, PolandEwa Mlicka-Kowalczyk1Dept. of Internal Medicine, Unit of Allergy and Clinical Immunology, Jagiellonian University Medical College, Krakow, PolandJacek Musial1Dept. of Internal Medicine, Unit of Allergy and Clinical Immunology, Jagiellonian University Medical College, Krakow, Poland
- Collagen receptors: α1β1 and α2β1 integrins may be involved in asthma pathogenesisBy Joanna Zuk, Stanislawa Bazan-Socha, Jacek Zarychta, Paulina Solarz and Jacek MusialJoanna Zuk1Department of Internal Medicine, Unit of Allergology and Clinical Immunology, Jagiellonian University Medical College, Cracow, PolandStanislawa Bazan-Socha1Department of Internal Medicine, Unit of Allergology and Clinical Immunology, Jagiellonian University Medical College, Cracow, PolandJacek Zarychta2Department of Internal Medicine, Division of Radiology, Jagiellonian University Medical College, Cracow, PolandPaulina Solarz3Unit of Allergology and Clinical Immunology, Jagiellonian University Medical College, Cracow, PolandJacek Musial1Department of Internal Medicine, Unit of Allergology and Clinical Immunology, Jagiellonian University Medical College, Cracow, Poland
- Combined analysis of gene expression and clinical data in the severe asthma U-BIOPRED cohortsBy Bertrand De Meulder, Diane Lefaudeux, Mansoor Saqi, Charles Auffray, Ian Adcock, Fan Chung, Jeanette Bigler, Matthew Loza, Navin Rao, Anthony Rowe, Frédéric Baribaud, Graham Roberts, Ana Sousa, Aruna Bansal, Chris Compton, David Myles, Ratko Djukanovic, Dominic Shaw, Ildiko Horvath, Jacek Musial, Julie Corfield, Pascal Chanez, Norbert Krug, Paolo Montuschi, Per Bakke, Peter Sterk, Riccardo Polosa, Scott Wager, Florian Singer, Stephen Fowler, Sven-Erik Dahlen, Thomas Sandström, Timothy Higenbottam, Ulf Nihlén, Urs Frey and Wolfgang SeiboldBertrand De Meulder1EISBM, CNRS, Lyon, Rhone, FranceDiane Lefaudeux1EISBM, CNRS, Lyon, Rhone, FranceMansoor Saqi1EISBM, CNRS, Lyon, Rhone, FranceCharles Auffray1EISBM, CNRS, Lyon, Rhone, FranceIan Adcock2National Heart & Lung Institute, Imperial College London, London, United KingdomFan Chung2National Heart & Lung Institute, Imperial College London, London, United KingdomJeanette Bigler3Amgen Inc, Amgen Inc, Seattle,Matthew Loza4Janssen Research and Development, Janssen, Springhouse,Navin Rao4Janssen Research and Development, Janssen, Springhouse,Anthony Rowe4Janssen Research and Development, Janssen, Springhouse,Frédéric Baribaud4Janssen Research and Development, Janssen, Springhouse,Graham Roberts5University Hospital Southampton NHS Foundation Trust, NHS Foundation Trust, Southampton, United KingdomAna Sousa6Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomAruna Bansal7Acclarogen, Acclarogen Ltd, Cambridge, United KingdomChris Compton8Respiratory Development, Novartis, Redhill, United KingdomDavid Myles6Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomRatko Djukanovic5University Hospital Southampton NHS Foundation Trust, NHS Foundation Trust, Southampton, United KingdomDominic Shaw9Nottingham University Hospital, Nottingham University Hospital, Nottingham, United KingdomIldiko Horvath10Semmelweis University, Semmelweis University, Budapest, HungaryJacek Musial11Allergy and Immunology, Jagiallonian University, Krakow, PolandJulie Corfield12Areteva, Areteva Ltd, Nottingham, United KingdomPascal Chanez13Clinique des Bronches, Allergie et Sommeil, Université de la Méditerranée, Marseille, FranceNorbert Krug14Immunology, Allergology and Clinical Inhalation, Fraunhofer Institute, Hannover, GermanyPaolo Montuschi15Pharmacology, Università Cattolica del Sacro Cuore, Roma, ItalyPer Bakke16Thoracic Medicine, Haukeland University Hospital, Bergen, SwedenPeter Sterk17Pulmonology, Academisch Medisch Centrum, Amsterdam, NetherlandsRiccardo Polosa18Internal Medicine and Clinical Immunology, University of Catania, Catania, ItalyScott Wager19BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumFlorian Singer20Paediatric Respiratory Medicine, University Hospital, Inselpital, Bern, SwitzerlandStephen Fowler21Respiratory Research Group, University of Manchester, Manchester, United KingdomSven-Erik Dahlen22Experimental Asthma and Allergy Research, Karolinska Institutet, Stockholm, SwedenThomas Sandström23Pulmonology, University Hospital, Umea, SwedenTimothy Higenbottam24Corporate Clinical Development, Chiesi Pharmaceutics Ltd, Cheadle, United KingdomUlf Nihlén25AstraZeneca R&D, AstraZeneca, Södertälje, SwedenUrs Frey20Paediatric Respiratory Medicine, University Hospital, Inselpital, Bern, SwitzerlandWolfgang Seibold26Boehringer Ingelheim, Boehringer Ingelheim Corporation, Ingelheim am Rhein, Germany
- Characteristics of the adult corticosteroid-dependent severe asthma in UBIOPRED consortiumBy A.R. Sousa, Ioannis Pandis, Yang Xian, Uruj Hoda, Anthony Rowe, Julie Corfield, Elizabeth Jeyasingham, Aruna Bansal, Wolfgang Seibold, Ariane Wagener, Per Bakke, Graham Roberts, Florian Singer, Urs Frey, Horváth Ildikó, Riccardo Polosa, Norbert Krug, Roelinde Middelveld, Sven-Erik Dahlen, Jacek Musial, David Gibeon, Louise Fleming, Stephen Fowler, Laurie Pahus, Dominic Shaw, Peter Howarth, David Myles, Chris Compton, Tim Higenbottam, Paolo Montuschi, Jorgen Vestbo, Ulf Nihlen, Thomas Sandström, Scott Wagers, Ratko Djukanovic, Elisabeth Bel, Peter Sterk and Fan ChungA.R. Sousa1Discovery Medicine, GlaxoSmithKline, London, United KingdomIoannis Pandis2NHLI and Discovery Sciences, Imperial College, London, United KingdomYang Xian2NHLI and Discovery Sciences, Imperial College, London, United KingdomUruj Hoda2NHLI and Discovery Sciences, Imperial College, London, United KingdomAnthony Rowe5R&D IT External Innovation, Janssen, San Diego,Julie Corfield4Biobanking, AstraZeneca, Nottingham, United KingdomElizabeth Jeyasingham1Discovery Medicine, GlaxoSmithKline, London, United KingdomAruna Bansal23Biostatistics, Acclarogen Ltd, Cambridge, United KingdomWolfgang Seibold20Pharmaceuticals, Boehringer Ingelheim, Ingelheim, GermanyAriane Wagener9Faculty of Medicine, Universiteit van Amsterdam, Amsterdam, NetherlandsPer Bakke18Department of Medicine, Universitetet i Bergen, Bergen, NorwayGraham Roberts3Respiratory Medicine, University of Southampton, Southampton, United KingdomFlorian Singer16Division of Paediatric Respiratory Medicine, University Hospital, Inselspital, Bern, SwitzerlandUrs Frey16Division of Paediatric Respiratory Medicine, University Hospital, Inselspital, Bern, SwitzerlandHorváth Ildikó13Department of Pulmonology, Semmelweis University, Budapest, HungaryRiccardo Polosa15Institute of Internal Medicine and Clinical Immunology, University of Catania, Catania, ItalyNorbert Krug14Department of Clinical Airway Research, Fraunhofer-Gesellschaft, Hamburg, GermanyRoelinde Middelveld22BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumSven-Erik Dahlen22BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumJacek Musial7Department of Medicine, Jagiellonian University, Krakow, PolandDavid Gibeon2NHLI and Discovery Sciences, Imperial College, London, United KingdomLouise Fleming2NHLI and Discovery Sciences, Imperial College, London, United KingdomStephen Fowler8Respiratory Research Group, University of Manchester, Manchester, United KingdomLaurie Pahus10Département des Maladies Respiratoires, Université de la Méditeranée Aix-Marseille II, Marseille, FranceDominic Shaw17Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, United KingdomPeter Howarth3Respiratory Medicine, University of Southampton, Southampton, United KingdomDavid Myles1Discovery Medicine, GlaxoSmithKline, London, United KingdomChris Compton6Pharmaceuticals, Novartis, Basel, SwitzerlandTim Higenbottam22BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumPaolo Montuschi11Facoltà di Medicina e Chirurgia, Universita Cattolica Del Sacro Cuore, Roma, ItalyJorgen Vestbo12Department of Respiratory Medicine, Hvidore Hospital, Hvidovre, DenmarkUlf Nihlen4Biobanking, AstraZeneca, Nottingham, United KingdomThomas Sandström19Pulmonary Medicine, Umeå University, Umeå, SwedenScott Wagers22BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumRatko Djukanovic3Respiratory Medicine, University of Southampton, Southampton, United KingdomElisabeth Bel9Faculty of Medicine, Universiteit van Amsterdam, Amsterdam, NetherlandsPeter Sterk9Faculty of Medicine, Universiteit van Amsterdam, Amsterdam, NetherlandsFan Chung2NHLI and Discovery Sciences, Imperial College, London, United Kingdom
- Clustering analysis of clinical variables in U-BIOPRED adult asthma cohortBy Diane Lefaudeux, Bertrand De Meulder, Kian Fan Chung, Graham Roberts, Matthew J. Loza, Frédéric Baribaud, Ana Sousa, Aruna T. Bansal, Anthony Rowe, Ioannis Pandis, Alun Bedding, Amphun Chaiboonchoe, Hassan Ahmed, Charles Auffray, Chris H. Compton, David Myles, Ratko Djukanovic, Dominic E. Shaw, Ildiko Horvath, Jacek Musial, Julie Corfield, Pascal Chanez, Norbert Krug, Paolo Montuschi, Per Bakke, Peter J. Sterk, Riccardo Polosa, Scott S. Wagers, Florian Singer, Stephen J. Fowler, Sven-Erik Dahlen, Thomas Sandström, Timothy Higenbottam, Ulf Nihlén, Urs Frey, Wolfgang Seibold and The U-BIOPRED Study GroupDiane Lefaudeux1EISBM, CNRS, Lyon, FranceBertrand De Meulder1EISBM, CNRS, Lyon, FranceKian Fan Chung2National Heart and Lung Institute, Imperial College London, London, United KingdomGraham Roberts3Faculty of Medicine, University of Southampton, Southampton, United KingdomMatthew J. Loza4Janssen R&D, Janssen, Springhouse,Frédéric Baribaud4Janssen R&D, Janssen, Springhouse,Ana Sousa5Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomAruna T. Bansal6Acclarogen, Acclarogen Ltd, Cambridge, United KingdomAnthony Rowe7Janssen, Janssen, Buckinghamshire, United KingdomIoannis Pandis8Department of Computing, Imperial College London, London, United KingdomAlun Bedding5Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomAmphun Chaiboonchoe1EISBM, CNRS, Lyon, FranceHassan Ahmed1EISBM, CNRS, Lyon, FranceCharles Auffray1EISBM, CNRS, Lyon, FranceChris H. Compton9Respiratory Development, Novartis Pharma, Redhill, United KingdomDavid Myles5Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomRatko Djukanovic10NIHR Respiratory BioMedical Research Unit, University of Southampton, Southampton, United KingdomDominic E. Shaw11Nottingham University Hospital, Nottingham University Hospital, Nottingham, United KingdomIldiko Horvath12Semmelweis University, Semmelweis University, Budapest, HungaryJacek Musial13Allergy and Immunology, Jagiellonian University, Krakow, PolandJulie Corfield14Areteva, Areteva Ltd, Nottingham, United KingdomPascal Chanez15Clinique des Bronches, Allergie et Sommeil, Université de la Méditerranée, Marseille, FranceNorbert Krug16Immunology, Allergology and Clinical Inhalation, Fraunhofer Institute, Hannover, GermanyPaolo Montuschi17Pharmacology, Università Cattolica del Sacro Cuore, Rome, ItalyPer Bakke18Thoracic Medicine, Haukeland University Hospital, Bergen, SwedenPeter J. Sterk19Academic Medical Center, University of Amsterdam, Amsterdam, NetherlandsRiccardo Polosa20Internal Medicine and clinical Immunology, University of Catania, Catania, ItalyScott S. Wagers21BioSci Consulting, BioSci Consulting, Maasmechelen, BelgiumFlorian Singer22Paediatric Respiratory Medicine, University Hospital, Inselspital, Bern, SwitzerlandStephen J. Fowler23Respiratory Research Group, University of Manchester, Manchester, United KingdomSven-Erik Dahlen24Experimental Asthma and Allergy Research, Karolinska Institutet, Stockhlom, SwedenThomas Sandström25Pulmonology, University Hospital, Umea, SwedenTimothy Higenbottam26Corporate Clinical Development, Chiesi Pharmaceutics Ltd, Cheadle, United KingdomUlf Nihlén27AstraZeneca R&D, AstraZeneca, Södertälje, SwedenUrs Frey22Paediatric Respiratory Medicine, University Hospital, Inselspital, Bern, SwitzerlandWolfgang Seibold28Boehringer Ingelheim, Boehringer Ingelheim Corporation, Ingelheim am Rhein, GermanyThe U-BIOPRED Study Group1EISBM, CNRS, Lyon, France
- Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohortBy Dominick E. Shaw, Ana R. Sousa, Stephen J. Fowler, Louise J. Fleming, Graham Roberts, Julie Corfield, Ioannis Pandis, Aruna T. Bansal, Elisabeth H. Bel, Charles Auffray, Chris H. Compton, Hans Bisgaard, Enrica Bucchioni, Massimo Caruso, Pascal Chanez, Barbro Dahlén, Sven-Erik Dahlen, Kerry Dyson, Urs Frey, Thomas Geiser, Maria Gerhardsson de Verdier, David Gibeon, Yi-ke Guo, Simone Hashimoto, Gunilla Hedlin, Elizabeth Jeyasingham, Pieter-Paul W. Hekking, Tim Higenbottam, Ildikó Horváth, Alan J. Knox, Norbert Krug, Veit J. Erpenbeck, Lars X. Larsson, Nikos Lazarinis, John G. Matthews, Roelinde Middelveld, Paolo Montuschi, Jacek Musial, David Myles, Laurie Pahus, Thomas Sandström, Wolfgang Seibold, Florian Singer, Karin Strandberg, Jorgen Vestbo, Nadja Vissing, Christophe von Garnier, Ian M. Adcock, Scott Wagers, Anthony Rowe, Peter Howarth, Ariane H. Wagener, Ratko Djukanovic, Peter J. Sterk and Kian Fan ChungArticle | Published in 2015 in European Respiratory JournalDominick E. Shaw1Respiratory Research Unit, University of Nottingham, Nottingham, UK44Joint first authorsAna R. Sousa2Respiratory Therapeutic Unit, GSK, Stockley Park, UK44Joint first authorsStephen J. Fowler3Respiratory and Allergy Research Group, University of Manchester, Manchester, UKLouise J. Fleming4National Heart and Lung Institute, Imperial College, London, UKGraham Roberts5NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, Southampton, UK6Faculty of Medicine, University of Southampton, Southampton, UK7The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, UKJulie Corfield8AstraZeneca R&D, Mölndal, Sweden9Areteva R&D, Nottingham, UKIoannis Pandis10Data Science Institute, South Kensington Campus, Imperial College London, London, UKAruna T. Bansal11Acclarogen Ltd, St John's Innovation Centre, Cambridge, UKElisabeth H. Bel12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsCharles Auffray13European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, FranceChris H. Compton2Respiratory Therapeutic Unit, GSK, Stockley Park, UKHans Bisgaard14Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkEnrica Bucchioni15Chiesi Pharmacueticals SPA, Parma, ItalyMassimo Caruso16Dept of Clinical and Experimental Medicine Hospital University, University of Catania, Catania, ItalyPascal Chanez17Département des Maladies Respiratoires, Laboratoire d'immunologie, Aix Marseille Université Marseille, Marseille, FranceBarbro Dahlén18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenSven-Erik Dahlen19The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenKerry Dyson20CROMSOURCE, Stirling, UKUrs Frey21University Children's Hospital Basel, Basel, SwitzerlandThomas Geiser22University Hospital Bern, Bern, SwitzerlandMaria Gerhardsson de Verdier8AstraZeneca R&D, Mölndal, SwedenDavid Gibeon4National Heart and Lung Institute, Imperial College, London, UKYi-ke Guo10Data Science Institute, South Kensington Campus, Imperial College London, London, UKSimone Hashimoto12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsGunilla Hedlin23Dept of Women's and Children's Health and Center for Allergy Research, Karolinska Institutet, Stockholm, SwedenElizabeth Jeyasingham24UK Clinical Operations, GSK, Stockley Park, UKPieter-Paul W. Hekking12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsTim Higenbottam25Allergy Therapeutics, West Sussex, UKIldikó Horváth26Dept of Pulmonology, Semmelweis University, Budapest, HungaryAlan J. Knox1Respiratory Research Unit, University of Nottingham, Nottingham, UKNorbert Krug27Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, GermanyVeit J. Erpenbeck28Translational Medicine - Respiratory Profiling, Novartis Institutes for BioMedical Research, Basel, SwitzerlandLars X. Larsson8AstraZeneca R&D, Mölndal, SwedenNikos Lazarinis18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenJohn G. Matthews29Respiratory and Allergic Diseases, Product Development Immunology, Genentech, San Francisco, CA, USARoelinde Middelveld20CROMSOURCE, Stirling, UKPaolo Montuschi30Faculty of Medicine, Catholic University of the Sacred Heart, Rome, ItalyJacek Musial31Dept of Medicine, Jagiellonian University Medical College, Krakow, PolandDavid Myles32Respiratory Therapy Area Unit, GlaxoSmithKline, Stevenage, UKLaurie Pahus33Assistance publique des Hôpitaux de Marseille, Hôpital NORD, Clinique des bronches, allergies et sommeil, Marseille, FranceThomas Sandström34Dept of Medicine, Dept of Public Health and Clinical Medicine Respiratory Medicine Unit, Umeå University, Umeå, SwedenWolfgang Seibold35Boehringer Ingelheim Pharma GmbH & Co., Ingelheim, GermanyFlorian Singer36University Children's Hospital Zurich, Zurich, SwitzerlandKarin Strandberg18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenJorgen Vestbo37Respiratory Research Group, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UKNadja Vissing38The Danish Pediatric Asthma Center, University of Copenhagen, Copenhagen, DenmarkChristophe von Garnier22University Hospital Bern, Bern, Switzerland39Tiefenau Hospital, Bern, SwitzerlandIan M. Adcock4National Heart and Lung Institute, Imperial College, London, UK40Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, UKScott Wagers41BioSci Consulting, Maasmechelen, BelgiumAnthony Rowe42Janssen Research and Development Ltd, High Wycombe, UKPeter Howarth43NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UKAriane H. Wagener12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsRatko Djukanovic43NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UKPeter J. Sterk12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands45Joint last authorsKian Fan Chung4National Heart and Lung Institute, Imperial College, London, UK40Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, UK45Joint last authors
- Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohortBy Dominick E. Shaw, Ana R. Sousa, Stephen J. Fowler, Louise J. Fleming, Graham Roberts, Julie Corfield, Ioannis Pandis, Aruna T. Bansal, Elisabeth H. Bel, Charles Auffray, Chris H. Compton, Hans Bisgaard, Enrica Bucchioni, Massimo Caruso, Pascal Chanez, Barbro Dahlén, Sven-Erik Dahlen, Kerry Dyson, Urs Frey, Thomas Geiser, Maria Gerhardsson de Verdier, David Gibeon, Yi-ke Guo, Simone Hashimoto, Gunilla Hedlin, Elizabeth Jeyasingham, Pieter-Paul W. Hekking, Tim Higenbottam, Ildikó Horváth, Alan J. Knox, Norbert Krug, Veit J. Erpenbeck, Lars X. Larsson, Nikos Lazarinis, John G. Matthews, Roelinde Middelveld, Paolo Montuschi, Jacek Musial, David Myles, Laurie Pahus, Thomas Sandström, Wolfgang Seibold, Florian Singer, Karin Strandberg, Jorgen Vestbo, Nadja Vissing, Christophe von Garnier, Ian M. Adcock, Scott Wagers, Anthony Rowe, Peter Howarth, Ariane H. Wagener, Ratko Djukanovic, Peter J. Sterk and Kian Fan ChungDominick E. Shaw1Respiratory Research Unit, University of Nottingham, Nottingham, UK44Joint first authorsAna R. Sousa2Respiratory Therapeutic Unit, GSK, Stockley Park, UK44Joint first authorsStephen J. Fowler3Respiratory and Allergy Research Group, University of Manchester, Manchester, UKLouise J. Fleming4National Heart and Lung Institute, Imperial College, London, UKGraham Roberts5NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, Southampton, UK6Faculty of Medicine, University of Southampton, Southampton, UK7The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, UKJulie Corfield8AstraZeneca R&D, Mölndal, Sweden9Areteva R&D, Nottingham, UKIoannis Pandis10Data Science Institute, South Kensington Campus, Imperial College London, London, UKAruna T. Bansal11Acclarogen Ltd, St John's Innovation Centre, Cambridge, UKElisabeth H. Bel12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsCharles Auffray13European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, FranceChris H. Compton2Respiratory Therapeutic Unit, GSK, Stockley Park, UKHans Bisgaard14Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkEnrica Bucchioni15Chiesi Pharmacueticals SPA, Parma, ItalyMassimo Caruso16Dept of Clinical and Experimental Medicine Hospital University, University of Catania, Catania, ItalyPascal Chanez17Département des Maladies Respiratoires, Laboratoire d'immunologie, Aix Marseille Université Marseille, Marseille, FranceBarbro Dahlén18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenSven-Erik Dahlen19The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenKerry Dyson20CROMSOURCE, Stirling, UKUrs Frey21University Children's Hospital Basel, Basel, SwitzerlandThomas Geiser22University Hospital Bern, Bern, SwitzerlandMaria Gerhardsson de Verdier8AstraZeneca R&D, Mölndal, SwedenDavid Gibeon4National Heart and Lung Institute, Imperial College, London, UKYi-ke Guo10Data Science Institute, South Kensington Campus, Imperial College London, London, UKSimone Hashimoto12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsGunilla Hedlin23Dept of Women's and Children's Health and Center for Allergy Research, Karolinska Institutet, Stockholm, SwedenElizabeth Jeyasingham24UK Clinical Operations, GSK, Stockley Park, UKPieter-Paul W. Hekking12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsTim Higenbottam25Allergy Therapeutics, West Sussex, UKIldikó Horváth26Dept of Pulmonology, Semmelweis University, Budapest, HungaryAlan J. Knox1Respiratory Research Unit, University of Nottingham, Nottingham, UKNorbert Krug27Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, GermanyVeit J. Erpenbeck28Translational Medicine - Respiratory Profiling, Novartis Institutes for BioMedical Research, Basel, SwitzerlandLars X. Larsson8AstraZeneca R&D, Mölndal, SwedenNikos Lazarinis18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenJohn G. Matthews29Respiratory and Allergic Diseases, Product Development Immunology, Genentech, San Francisco, CA, USARoelinde Middelveld20CROMSOURCE, Stirling, UKPaolo Montuschi30Faculty of Medicine, Catholic University of the Sacred Heart, Rome, ItalyJacek Musial31Dept of Medicine, Jagiellonian University Medical College, Krakow, PolandDavid Myles32Respiratory Therapy Area Unit, GlaxoSmithKline, Stevenage, UKLaurie Pahus33Assistance publique des Hôpitaux de Marseille, Hôpital NORD, Clinique des bronches, allergies et sommeil, Marseille, FranceThomas Sandström34Dept of Medicine, Dept of Public Health and Clinical Medicine Respiratory Medicine Unit, Umeå University, Umeå, SwedenWolfgang Seibold35Boehringer Ingelheim Pharma GmbH & Co., Ingelheim, GermanyFlorian Singer36University Children's Hospital Zurich, Zurich, SwitzerlandKarin Strandberg18Lung/Allergy Clinic, Karolinska University Hospital Huddinge, Stockholm, SwedenJorgen Vestbo37Respiratory Research Group, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UKNadja Vissing38The Danish Pediatric Asthma Center, University of Copenhagen, Copenhagen, DenmarkChristophe von Garnier22University Hospital Bern, Bern, Switzerland39Tiefenau Hospital, Bern, SwitzerlandIan M. Adcock4National Heart and Lung Institute, Imperial College, London, UK40Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, UKScott Wagers41BioSci Consulting, Maasmechelen, BelgiumAnthony Rowe42Janssen Research and Development Ltd, High Wycombe, UKPeter Howarth43NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UKAriane H. Wagener12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The NetherlandsRatko Djukanovic43NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UKPeter J. Sterk12Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands45Joint last authorsKian Fan Chung4National Heart and Lung Institute, Imperial College, London, UK40Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, UK45Joint last authors
- The first U-BIOPRED blood handprint of severe asthmaBy Bertrand De Meulder, Diane Lefaudeux, Jeanette Bigler, Matthew J. Loza, Craig E. Wheelock, Ana R. Sousa, Julie Corfield, Frédéric Baribaud, Charles Auffray, Dominic E. Shaw, Ildiko Horvath, Jacek Musial, Pascal Chanez, Norbert Krug, Paolo Montuschi, Per S. Bakke, Florian Singer, Stephen J. Fowler, Sven-Erik Dahlen, Thomas Sandström, Peter J. Sterk, Kian Fan Chung, Ian M. Adcock, Ratko Djukanovic and The U-BIOPRED Working GroupBertrand De Meulder1European Institute for Systems Biology and Medicine (EISBM), CNRS - ENS - UCBL Université de Lyon, Lyon, Rhone FranceDiane Lefaudeux1European Institute for Systems Biology and Medicine (EISBM), CNRS - ENS - UCBL Université de Lyon, Lyon, Rhone FranceJeanette Bigler2Amgen, Amgen, Seattle, United StatesMatthew J. Loza3Systems Pharmacology and Biomarkers, Janssen R&D, Springhouse, United StatesCraig E. Wheelock4Bioanalytical Chemistry Research Laboratory in Inflammatory Metabolomics, Karolinska Institutet, Stockholm, SwedenAna R. Sousa5Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomJulie Corfield6Arateva, Arateva Ltd., Nottingham, United KingdomFrédéric Baribaud3Systems Pharmacology and Biomarkers, Janssen R&D, Springhouse, United StatesCharles Auffray1European Institute for Systems Biology and Medicine (EISBM), CNRS - ENS - UCBL Université de Lyon, Lyon, Rhone FranceDominic E. Shaw7Faculty of Medicine and Health Sciences, Nottingham University Hospital, Nottingham, United KingdomIldiko Horvath8Pulmonology, Semmelweis University, Budapest, HungaryJacek Musial9Allergy and Immunology, Jagiellonian University, Krakow, PolandPascal Chanez10Clinique des Bronches, Allergie et Sommeil, Université de la Méditerranée, Marseille, FranceNorbert Krug11Immunology, Allergology and Clinical Inhalation, Fraunhofer Institute, Hannover, GermanyPaolo Montuschi12Pharmacology, Unniversità Cattolica del Sacro Cuore, Roma, ItalyPer S. Bakke13Thoracic Medicine, Haukeland University Hospital, Bergen, NorwayFlorian Singer14Paediatric Respiratory Medicine, University Hospital, Inselpital, Bern, SwitzerlandStephen J. Fowler15Respiratory Research Group, University of Manchester, Manchester, United KingdomSven-Erik Dahlen16Experimental Asthma and Allergy Research, Karolinska Institutet, Stockholm, SwedenThomas Sandström17Pulmonology, University Hospital, Umea, SwedenPeter J. Sterk18Pulmonology, Academisch Medisch Centrum, Amsterdam, NetherlandsKian Fan Chung19National Hearth & Lung Institute, Imperial College London, London, United KingdomIan M. Adcock19National Hearth & Lung Institute, Imperial College London, London, United KingdomRatko Djukanovic20National Institute for Health Research Respiratory Biomedical Research Unit, University of Southampton, Southampton, United Kingdom1European Institute for Systems Biology and Medicine (EISBM), CNRS - ENS - UCBL Université de Lyon, Lyon, Rhone France
- Induced sputum supernatant eicosanoids during oral aspirin challenge of asthmatic patients with and without aspirin hypersensitivity and healthy controlsBy Maria Ignacak, Natalia Celejewska-Wojcik, Krzysztof Wojcik, Aleksandra Cholewa, Kinga Salapa, Krzysztof Oles, Krzysztof Sladek, Jacek Musial and Lucyna MastalerzMaria IgnacakDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandNatalia Celejewska-WojcikDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandKrzysztof WojcikDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandAleksandra CholewaDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandKinga SalapaDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandKrzysztof OlesDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandKrzysztof SladekDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandJacek MusialDepartment of Medicine, Jagiellonian University Medical College, Krakow, PolandLucyna MastalerzDepartment of Medicine, Jagiellonian University Medical College, Krakow, Poland
- The first U-BIOPRED sputum handprint of severe asthmaBy Diane Lefaudeux, Bertrand De Meulder, Matthew J. Loza, Marek Sanak, Ana R. Sousa, Julie Corfield, Frédéric Baribaud, Dominic E. Shaw, Ildiko Horvath, Jacek Musial, Pascal Chanez, Norbert Krug, Paolo Montuschi, Per S. Bakke, Florian Singer, Stephen J. Fowler, Sven-Erik Dahlén, Thomas Sandström, Peter J. Sterk, Ratko Djukanovic, Kian Fan Chung, Ian M. Adcock, Charles Auffray and The U-BIOPRED Study GroupDiane Lefaudeux1EISBM, CNRS - ENS - UCBL, Lyon, FranceBertrand De Meulder1EISBM, CNRS - ENS - UCBL, Lyon, FranceMatthew J. Loza2Systems Pharmacology & Biomarkers, Janssen Research and Development, Springhouse, United StatesMarek Sanak3'Molecular Biology and Clinical Genetics' and 'Allergy and Immunology', Jagiellonian University Medical College, Krakow, PolandAna R. Sousa4Discovery Medicine, GlaxoSmithKline, Uxbridge, United KingdomJulie Corfield5Areteva, Arateva Ltd, Nottingham, United KingdomFrédéric Baribaud2Systems Pharmacology & Biomarkers, Janssen Research and Development, Springhouse, United StatesDominic E. Shaw6Faculty of Medicine & Health Sciences, Nottingham University Hospital, Nottingham, United KingdomIldiko Horvath7Pulmonology, Semmelweis University, Budapest, HungaryJacek Musial3'Molecular Biology and Clinical Genetics' and 'Allergy and Immunology', Jagiellonian University Medical College, Krakow, PolandPascal Chanez8Clinique des Bronches, Allergie et Sommeil, Université de la Méditerranée, Marseille, FranceNorbert Krug9Immunology, Allergology and Clinical Inhalation, Fraunhofer Institute, Hannover, GermanyPaolo Montuschi10Pharmacology, Università Cattolica del Sacro Cuore, Roma, ItalyPer S. Bakke11Thoracic Medicine, Haukeland University Hospital, Bergen, NorwayFlorian Singer12Pulmonology, University Hospital, Inselspital, Bern, SwitzerlandStephen J. Fowler13Respiratory Research Group, University of Manchester, Manchester, SwedenSven-Erik Dahlén14Experimental Asthma and Allergy Research, Karolinska Institutet, Stockholm, SwedenThomas Sandström15Pulmonology, University Hospital, Umea, SwedenPeter J. Sterk16Academic Medical Center, University of Amsterdam, Amsterdam, NetherlandsRatko Djukanovic17NHS Foundation Trust, University Hospital Southampton, Southampton, United KingdomKian Fan Chung18National Heart & Lung Institute, Imperial College London, London, United KingdomIan M. Adcock18National Heart & Lung Institute, Imperial College London, London, United KingdomCharles Auffray1EISBM, CNRS - ENS - UCBL, Lyon, France1EISBM, CNRS - ENS - UCBL, Lyon, France
- Characteristics of the frequent exacerbator in U-BIOPRED adult severe asthma cohortBy Uruj Hoda, Ana Sousa, Julie Corfield, Dominic Shaw, Stephen Fowler, Louise Fleming, Wolfgang Seibold, Per Bakke, Christophe Von Garnier, Ildikó Horváth, Norbert Krug, Barbro Dahlen, Jacek Musial, Pascal Chanez, Paolo Montuschi, Thomas Sandstrom, Peter Howarth, Elisabeth Bel, Aruna Bansal, Ioannis Pandis, Chih-Hsi Kuo, Ratko Djukanovic, Peter Sterk, Graham Roberts, Fan Chung, Fan Chung and U-BIOPRED Study GroupUruj Hoda1NHLI, Imperial College London, London, United KingdomAna Sousa2Respiratory Therapy Unit, GlaxoSmithKline, London, United KingdomJulie Corfield3Clinical Research, AstraZeneca, Mölndal, SwedenDominic Shaw4Nottingham Respiratory Research Unit, Nottingham City Hospital, Nottingham, United KingdomStephen Fowler5Respiratory Medicine, University of Manchester and Lancashire Teaching Hospitals NHS Foundation Trust, Manchester, United KingdomLouise Fleming1NHLI, Imperial College London, London, United KingdomWolfgang Seibold6Global Clinical Operations, Boehringer Ingelheim Pharma GmbH & Co. KG, 8Global Clinical Operations, Boehringer Ingelheim, Ingelheim am Rhein GermanyPer Bakke8Respiratory, Haukeland University Hospital, Bergen, NorwayChristophe Von Garnier9Respiratory, Inselspital and University of Bern, Bern, SwitzerlandIldikó Horváth10Department of Pulmonology, Semmelweis University, Budapest, HungaryNorbert Krug11Medicine, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, GermanyBarbro Dahlen12The Centre for Allergy Research, Karolinska Institute, Stockholm, SwedenJacek Musial13Medical College, Jagiellonian University, Krakow, PolandPascal Chanez14Hopital Nord, Bureau de Recherche Clinique, Université de la Méditerranee, Marseille, FrancePaolo Montuschi15Istituto di Farmacologia, Università Cattolica del Sacro Cuore, Rome, ItalyThomas Sandstrom16Respiratory and Allergy Division, University Hospital, Umeå, Umeå, SwedenPeter Howarth7Faculty of Medicine, University of Southampton, Southampton, United KingdomElisabeth Bel17Academic Medical Centre, University of Amsterdam, Amsterdam, NetherlandsAruna Bansal18Acclarogen, Acclarogen Ltd, Cambridge, United KingdomIoannis Pandis1NHLI, Imperial College London, London, United KingdomChih-Hsi Kuo1NHLI, Imperial College London, London, United KingdomRatko Djukanovic7Faculty of Medicine, University of Southampton, Southampton, United KingdomPeter Sterk17Academic Medical Centre, University of Amsterdam, Amsterdam, NetherlandsGraham Roberts7Faculty of Medicine, University of Southampton, Southampton, United KingdomFan Chung1NHLI, Imperial College London, London, United KingdomFan Chung1NHLI, Imperial College London, London, United Kingdom1NHLI, Imperial College London, London, United Kingdom
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The ERS Monograph is the quarterly book series from the European Respiratory Society. Each Monograph covers a specific area of respiratory medicine, providing in-depth reviews that give clinicians at all levels a concise, comprehensive guide to symptoms, diagnosis and treatment.
The ERS Handbooks are compact guides to broad areas of the respiratory field. Launched in 2010, the series now covers adult, paediatric and sleep respiratory medicine, includes a companion volume of self-assessment questions and features the ERS Practical Handbooks.