William MacNee
- COPD and ComorbidityEdited by Klaus F. Rabe, Jadwiga A. Wedzicha and Emiel F.M. WoutersBook | Published in 2013DOI: 10.1183/1025448x.erm5913ISBN (electronic): 978-1-84984-033-0Klaus F. RabeJadwiga A. Wedzicha
- Metabolic profiling detects biomarkers of protein degradation in COPD patientsBy Baljit K. Ubhi, John H. Riley, Paul A. Shaw, David A. Lomas, Ruth Tal-Singer, William MacNee, Julian L. Griffin and Susan C. ConnorBaljit K. Ubhi*Dept of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge,John H. Riley#Respiratory MDC, GlaxoSmithKline, StevenagePaul A. Shaw¶Dept of Investigative Preclinical Toxicology, Safety Assessment Division, GlaxoSmithKline R&D, WareDavid A. Lomas+Dept of Medicine, University of Cambridge, Cambridge Institute for Medical Research, CambridgeRuth Tal-Singer§GlaxoSmithKline R&D, King of Prussia, PA, USAWilliam MacNeefCentre for Inflammation Research, Queen’s Medical Research Institute, Edinburgh, UKJulian L. Griffin*Dept of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge,Susan C. Connor*Dept of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge,
- The European Respiratory Society spirometry tent: a unique form of screening for airway obstructionBy Sara Maio, Duane L. Sherrill, William MacNee, Peter Lange, Ulrich Costabel, Sven-Erik Dahlén, Gerhard W. Sybrecht, Otto C. Burghuber, Robin Stevenson, Philip Tønnesen, Karl Haeussinger, Gunilla Hedlin, Torsten T. Bauer, Josef Riedler, Laurent Nicod, Kai-Håkon Carlsen and Giovanni ViegiSara MaioDuane L. SherrillWilliam MacNeePeter LangeUlrich CostabelSven-Erik DahlénGerhard W. SybrechtOtto C. BurghuberRobin StevensonPhilip TønnesenKarl HaeussingerGunilla HedlinTorsten T. BauerJosef RiedlerLaurent NicodKai-Håkon Carlsen
- Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPDBy David A. McAllister, John D. Maclay, Nicholas L. Mills, Andrew Leitch, Philip Reid, Ross Carruthers, Jennifer O’Connor, Lawrence McAlpine, George Chalmers, David E. Newby, Elaine Clark, Peter W. Macfarlane and William MacNeeDavid A. McAllisterJohn D. MaclayNicholas L. MillsAndrew LeitchPhilip ReidRoss CarruthersJennifer O’ConnorLawrence McAlpineGeorge ChalmersDavid E. NewbyElaine ClarkPeter W. MacfarlaneWilliam MacNee
- Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohortBy Alvar Agusti, Lisa D. Edwards, Bartolomé Celli, William MacNee, Peter M. A. Calverley, Hana Müllerova, David A. Lomas, Emiel Wouters, Per Bakke, Steve Rennard, Courtney Crim, Bruce E. Miller, Harvey O. Coxson, Julie C. Yates, Ruth Tal-Singer and Jørgen VestboAlvar Agusti1Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias, FISIB, Mallorca, SpainLisa D. Edwards2GlaxoSmithKline, Research Triangle Park, NCBartolomé Celli3Dept of Respiratory Medicine; Brigham and Women's Hospital, Boston, MAWilliam MacNee4University of Edinburgh & Royal Infirmary, EdinburghPeter M. A. Calverley5Dept of Respiratory Medicine, University Hospital Aintree, LiverpoolHana Müllerova6Epidemiology, GlaxoSmithKline R&D, MiddlesexDavid A. Lomas7Dept of Medicine, University of Cambridge, Cambridge Institute for Medical Research, CambridgeEmiel Wouters8Dept of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The NetherlandsPer Bakke9Institute of Medicine, University of Bergen, Bergen10Dept of Thoracic Medicine, Haukeland University Hospital, Bergen, NorwaySteve Rennard11University of Nebraska Medical Center, Omaha, NECourtney Crim2GlaxoSmithKline, Research Triangle Park, NCBruce E. Miller12GlaxoSmithKline, King of Prussia, PA, USAHarvey O. Coxson13Dept of Radiology, University of British Columbia, Vancouver General Hospital, Vancouver, BC, CanadaJulie C. Yates2GlaxoSmithKline, Research Triangle Park, NCRuth Tal-Singer12GlaxoSmithKline, King of Prussia, PA, USAJørgen Vestbo14Dept of Respiratory Medicine, Odense University Hospital/University of Southern Denmark, Denmark15Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
- Validity of physical activity monitors during daily life in patients with COPDBy Roberto A. Rabinovich, Zafeiris Louvaris, Yogini Raste, Daniel Langer, Hans Van Remoortel, Santiago Giavedoni, Chris Burtin, Eloisa M.G. Regueiro, Ioannis Vogiatzis, Nicholas S. Hopkinson, Michael I. Polkey, Frederick J. Wilson, William MacNee, Klaas R. Westerterp and Thierry TroostersRoberto A. Rabinovich1ELEGI Colt Laboratory, Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh8Both authors contributed equallyZafeiris Louvaris2Dept of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, M. Simou and G.P. Livanos Laboratories, National and Kapodistrian University of Athens, Thorax Foundation, Athens, Greece8Both authors contributed equallyYogini Raste3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart and Lung Institute, Imperial College London, LondonDaniel Langer4Dept of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumHans Van Remoortel4Dept of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumSantiago Giavedoni1ELEGI Colt Laboratory, Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, EdinburghChris Burtin4Dept of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumEloisa M.G. Regueiro5Laboratory of Respiratory Physiotherapy, Universidade Federal de São Carlos (UFSCar), São Carlos, BrazilIoannis Vogiatzis2Dept of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, M. Simou and G.P. Livanos Laboratories, National and Kapodistrian University of Athens, Thorax Foundation, Athens, GreeceNicholas S. Hopkinson3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart and Lung Institute, Imperial College London, LondonMichael I. Polkey3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart and Lung Institute, Imperial College London, LondonFrederick J. Wilson6Precision Medicine, Pfizer Worldwide Research and Development, Sandwich, UKWilliam MacNee1ELEGI Colt Laboratory, Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, EdinburghKlaas R. Westerterp7Dept of Human Biology, Maastricht University, Maastricht, The NetherlandsThierry Troosters4Dept of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
- Pleiotropic effects of add-on atorvastatin therapy during the treatment of COPD patientsBy Robert Mroz, Agnieszka Tycinska, Lukasz Minarowski, Joanna Bierla, Pawel Lisowski, Bozena Sobkowicz, Elzbieta Chyczewska, Wlodzimierz Musial and William MacNeeRobert Mroz1Pneumology Department, Medical University of Bialystok, Bialystok, PolandAgnieszka Tycinska2Cardiology Department, Medical University of Bialystok, Bialystok, PolandLukasz Minarowski1Pneumology Department, Medical University of Bialystok, Bialystok, PolandJoanna Bierla3Department of Physiological Sciences, Warsaw University of Life Sciences - SGGW, Warsaw, PolandPawel Lisowski4Department of Molecular Biology, Institute of Genetics and Animal Breeding, Jastrzebiec n/Warsaw, PolandBozena Sobkowicz2Cardiology Department, Medical University of Bialystok, Bialystok, PolandElzbieta Chyczewska1Pneumology Department, Medical University of Bialystok, Bialystok, PolandWlodzimierz Musial2Cardiology Department, Medical University of Bialystok, Bialystok, PolandWilliam MacNee5ELEGI Colt Research Labs, UoE/MRC Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh, United Kingdom
- Validity of activity monitors for physical activity assessment in patients with chronic obstructive pulmonary diseaseBy Roberto Rabinovich, Zafeiris Louvaris, Yogini Raste, Daniel Langer, Hans Van Remoortel, Santiago Giavedoni, Chris Burtin, Eloisa Regueiro, Ioannis Vogiatzis, Nicholas Hopkinson, Michael Polkey, Frederik Wilson, William MacNee, Klass Westerterp and Thierry TroostersRoberto Rabinovich1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomZafeiris Louvaris2Department of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, National & Kapodistrian, University of Athens, GreeceYogini Raste3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomDaniel Langer4Faculty of Kinesiology and Rehabilitation Sciences, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, BelgiumHans Van Remoortel4Faculty of Kinesiology and Rehabilitation Sciences, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, BelgiumSantiago Giavedoni1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomChris Burtin4Faculty of Kinesiology and Rehabilitation Sciences, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, BelgiumEloisa Regueiro5UFSCar, São Carlos, Universidade Federal de São Carlos, BrazilIoannis Vogiatzis2Department of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, National & Kapodistrian, University of Athens, GreeceNicholas Hopkinson3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomMichael Polkey3NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomFrederik Wilson6Precision Medicine, Pfizer Worldwide Research and Development, Pfizer, Kent, United KingdomWilliam MacNee1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomKlass Westerterp7Department of Human Biology, Maastricht University, Maastricht, NetherlandsThierry Troosters4Faculty of Kinesiology and Rehabilitation Sciences, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Belgium
- Clinical impact of anaemia in patients with chronic obstructive pulmonary disease: Results from ECLIPSE studyBy Mitja Lainscak, Lisa Edwards, Stefan Anker, Courtney Crim, Stephen Rennard, Emiel Wouters and William MacNeeMitja Lainscak1Division of Cardiology, University Clinic of Pulmonary and Allergic Diseases, Golnik, Slovenia2Applied Cachexia Research, Charite Universitaetsmedizin Berlin, Berlin, GermanyLisa Edwards3Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, PA, United StatesStefan Anker2Applied Cachexia Research, Charite Universitaetsmedizin Berlin, Berlin, GermanyCourtney Crim3Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, PA, United StatesStephen Rennard4Pulmonary and Critical Care Medicine, University of Nebraska Medical Center, Omaha, United StatesEmiel Wouters5Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, NetherlandsWilliam MacNee6MRC Centre for Inflammation Research, University of Edinburgh, United Kingdom
- Low CT bone radio density is associated with adverse clinical features and increased coronary artery calcification in COPDBy Elisabeth Romme, Lisa Edwards, MIchelle Williams, John Murchison, Martin Connell, Alvar Agusti, Stephen Rennard, Per Bakke, Frank Smeenk, Emiel Wouters, Erica Rutten and William MacNeeElisabeth Romme1Department of Respiratory Medicine, Catharina Hospital, Eindhoven, NetherlandsLisa Edwards2Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, United StatesMIchelle Williams3Centre for Cardiovascular Science, University of Edinburgh, United KingdomJohn Murchison4Department of Radiology, Royal Infirmary of Edinburgh, United KingdomMartin Connell5Clinical Research Imaging Centre, University of Edinburgh, United KingdomAlvar Agusti6Institut Clínic del Tòrax, Universitat de Barcelona, SpainStephen Rennard7Pulmonary and Critical Care Medicine, University of Nebraska Medical Cente, Omaha, United StatesPer Bakke8Department of Thoracic Medicine, University of Bergen/Haukeland University Hospital, Bergen, NorwayFrank Smeenk1Department of Respiratory Medicine, Catharina Hospital, Eindhoven, NetherlandsEmiel Wouters9Department of Respiratory Medicine, University Hospital, Maastricht, NetherlandsErica Rutten10Program Development Centre, Centre of Expertise for Chronic Organ Failure, Eindhoven, NetherlandsWilliam MacNee11MRC Centre for Inflammation Research, University of Edinburgh, United Kingdom
- Coronary artery calcification in COPD is associated with adverse functional assessments and mortalityBy Michelle Williams, Lisa Edwards, Ruth Tal-Singer, Bruce Miller, John Murchison, Edwin van Beek, David Newby and William MacNeeMichelle Williams1Centre for Cardiovascular Science, University of Edinburgh, United KingdomLisa Edwards2Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, PA, United StatesRuth Tal-Singer2Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, PA, United StatesBruce Miller2Respiratory CEDD Discovery Medicine, GlaxoSmithKline, Philadelphia, PA, United StatesJohn Murchison3Department of Radiology, Royal Infirmary of Edinburgh, United KingdomEdwin van Beek4Clinical Research Imaging Centre, University of Edinburgh, United KingdomDavid Newby1Centre for Cardiovascular Science, University of Edinburgh, United KingdomWilliam MacNee5MRC Centre for Inflammation Research, University of Edinburgh, United Kingdom
- The minimal clinically important difference (MCID) for the six minute walk (6MW) test in COPD in relation to deathBy Michael Polkey, Martijn Spruit, Lisa Edwards, Michael Watkins, Vincent Pinto-Plata, Jørgen Vestbo, Peter Calverley, Ruth Tal-Singer, Alvar Agusti, Per Bakke, Harvey Coxson, David Lomas, William MacNee, Stephen Rennard, Edwin Silverman, Bruce Miller, Courtney Crim, Julie Yates, Emiel Wouters and Bartholeme CelliMichael Polkey1Consultant Physician, Royal Brompton Hospital, London, United KingdomMartijn Spruit2Program Development Centre, CIRO+, a Centre of Expertise for Chronic Organ Failure, Horn, NetherlandsLisa Edwards3GSK, GlaxoSmithKline, Research Triangle Park,, NC, United StatesMichael Watkins3GSK, GlaxoSmithKline, Research Triangle Park,, NC, United StatesVincent Pinto-Plata4Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United StatesJørgen Vestbo5Respiratory Medicine, University of Manchester, United KingdomPeter Calverley6Department of Respiratory Medicine, School of Clinical Science, University of Liverpool, United KingdomRuth Tal-Singer7Galaxy Initiative, GlaxoSmithKline, King of Prussia, PA, United StatesAlvar Agusti8Institut del Tòrax, Hospital Clínic, IDIBAPS, CIBER Enfermedades Respiratorias and Fundación Caubet-Cimera, Barcelona, SpainPer Bakke9Institute of Medicine, University of Bergen, NorwayHarvey Coxson10Department of Radiology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, CanadaDavid Lomas11Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, United KingdomWilliam MacNee12ELEGI Colt Research Labs, University of Edinburgh/MRC Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh, United KingdomStephen Rennard13Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of Nebraska Medical Center, Omaha, NE, United StatesEdwin Silverman14Channing Laboratory, Brigham & Women's Hospital, Boston, MA, United StatesBruce Miller7Galaxy Initiative, GlaxoSmithKline, King of Prussia, PA, United StatesCourtney Crim3GSK, GlaxoSmithKline, Research Triangle Park,, NC, United StatesJulie Yates3GSK, GlaxoSmithKline, Research Triangle Park,, NC, United StatesEmiel Wouters2Program Development Centre, CIRO+, a Centre of Expertise for Chronic Organ Failure, Horn, NetherlandsBartholeme Celli4Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States
- Reduced mitochondrial density in the vastus lateralis muscle of COPD patients with low fat free massBy Santiago Giavedoni, Ellen Drost, Ramzi Lakhdar, William MacNee and Roberto RabinovichSantiago Giavedoni1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomEllen Drost1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomRamzi Lakhdar1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomWilliam MacNee1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United KingdomRoberto Rabinovich1ELEGI Colt Laboratory, Centre for Inflammation Research, the Queen's Medical Research Institute, The University of Edinburgh, Scotland, United Kingdom
- Does adding telemonitoring to optimised management of chronic obstructive pulmonary disease (COPD) reduce hospital admissions? Randomised controlled trialBy Hilary Pinnock, Lucy McCloughan, Allison Todd, Janet Hanley, Stephanie Lewis, Ashma Krishan, William MacNee, Claudia Pagliari, Aziz Sheikh and Brian McKinstryHilary Pinnock1Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomLucy McCloughan2eHealth Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomAllison Todd2eHealth Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomJanet Hanley3Nursing Midwifery and Social Care, Edinburgh Napier University, Edinburgh, United KingdomStephanie Lewis4Edinburgh Clinical Trials Unit, The University of Edinburgh, Edinburgh, United KingdomAshma Krishan4Edinburgh Clinical Trials Unit, The University of Edinburgh, Edinburgh, United KingdomWilliam MacNee5Edinburgh Lung and the Environment Group Initiative, The University of Edinburgh, Edinburgh, United KingdomClaudia Pagliari2eHealth Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomAziz Sheikh1Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomBrian McKinstry2eHealth Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United Kingdom
- Anti-inflammatory effects of add-on atorvastatin therapy during the treatment of COPD patientsBy Robert Mroz, Agnieszka Tycinska, Pawel Lisowski, Joanna Bierla, Lukasz Minarowski, Robert Milewski, Anna Lisowska, Piotr Boros, Elzbieta Chyczewska and William MacNeeRobert Mroz1Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, PolandAgnieszka Tycinska2Department of Cardiology, Medical University of Bialystok, PolandPawel Lisowski3Department of Molecular Biology, Institute of Genetics and Animal Breeding, Jastrzebiec n/Warsaw, PolandJoanna Bierla4Department of Physiology and Pathophysiology, Medical University of Warsaw, PolandLukasz Minarowski1Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, PolandRobert Milewski5Department of Statistics and Medical Informatics, Medical University of Bialystok, PolandAnna Lisowska2Department of Cardiology, Medical University of Bialystok, PolandPiotr Boros6Lung Function Laboratory, National Institute of Tuberculosis and Lung Diseases, Warsaw, PolandElzbieta Chyczewska1Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, PolandWilliam MacNee7ELEGI Colt Research Labs, UoE/MRC Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh, United Kingdom
- ERICA (evaluating the role of inflammation in chronic airways disease): Extrapulmonary manifestations of COPDBy Divya Mohan, Carmel McEniery, Nicola Gale, Jonathan Fuld, Charlotte Bolton, William MacNee, Peter Calverley, Ruth Tal-Singer, Ian Wilkinson, Michael Polkey and John CockcroftDivya Mohan1NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, United KingdomCarmel McEniery2Clinical Pharmacology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, United KingdomNicola Gale3Department of Cardiology, Wales Heart Research Institute, University Hospital Wales, Cardiff, United KingdomJonathan Fuld4Department of Respiratory Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United KingdomCharlotte Bolton5Nottingham Respiratory Research Unit, University of Nottingham, Nottingham, United KingdomWilliam MacNee6MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United KingdomPeter Calverley7Department of Respiratory Medicine, University of Liverpool, Liverpool, United KingdomRuth Tal-Singer8Respiratory Therapy Area Unit, GlaxoSmithKline, King of Prussia, United StatesIan Wilkinson2Clinical Pharmacology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, United KingdomMichael Polkey1NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, United KingdomJohn Cockcroft3Department of Cardiology, Wales Heart Research Institute, University Hospital Wales, Cardiff, United Kingdom
- HELPing people with very severe COPD: Feasibility study of a novel holistic interventionBy Susan Buckingham, Marilyn Kendall, Susie Ferguson, Aziz Sheikh, Scott A. Murrray, William MacNee, Patrick White, Allison Worth, Kirsty Boyd and Hilary PinnockSusan Buckingham1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomMarilyn Kendall1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomSusie Ferguson1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomAziz Sheikh1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomScott A. Murrray1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomWilliam MacNee2Centre for Inflammation Research, University of Edinburgh, Edinburgh, United KingdomPatrick White3Department of Primary Care and Public Health Sciences, King's College London, London, United KingdomAllison Worth1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomKirsty Boyd1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomHilary Pinnock1Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
- Associations between arterial calcification and stiffness, bone density, emphysema and all-cause mortality in COPD patientsBy Elisabeth Romme, David McAllister, John Murchison, Edwin Van Beek, George Petrides, Erica Rutten, Frank Smeenk, Emiel Wouters and William MacNeeElisabeth Romme1Respiratory Medicine, Catharina Hospital, Eindhoven, Netherlands2Respiratory Medicine, Maastricht University Medical Centre+, Maastricht, NetherlandsDavid McAllister3Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomJohn Murchison4Radiology, Royal Infirmary of Edinburgh, Edinburgh, United KingdomEdwin Van Beek5Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, United KingdomGeorge Petrides6Radiology, Newcastle University Teaching Hospitals, Newcastle upon Tyne, United KingdomErica Rutten7Program Development Centre, Centre of Expertise for Chronic Organ Failure, Horn, NetherlandsFrank Smeenk1Respiratory Medicine, Catharina Hospital, Eindhoven, NetherlandsEmiel Wouters2Respiratory Medicine, Maastricht University Medical Centre+, Maastricht, NetherlandsWilliam MacNee8Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom
- A low sputum MMP-9 activity/TIMP ratio is associated with CT airway wall thickness in smokers with asthmaBy Rekha Chaudhuri, Charles McSharry, Jeffrey Brady, Christal Grierson, Claudia-Martina Messow, Mark Spears, Karl Nocka, William MacNee, Martin Connell, John Murchison, Michael Sproule, Douglas Miller and Neil ThomsonRekha Chaudhuri1Respiratory Medicine; Infection, Inflammation, Immunity, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomCharles McSharry1Respiratory Medicine; Infection, Inflammation, Immunity, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomJeffrey Brady2Translational Medicine Research Collaboration, Pfizer Research, Dundee, United KingdomChristal Grierson2Translational Medicine Research Collaboration, Pfizer Research, Dundee, United KingdomClaudia-Martina Messow3Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United KingdomMark Spears1Respiratory Medicine; Infection, Inflammation, Immunity, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomKarl Nocka4Translational Medicine Research Collaboration, Pfizer Research, Cambridge MA & Collegeville, PA, United StatesWilliam MacNee5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomMartin Connell5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomJohn Murchison5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomMichael Sproule1Respiratory Medicine; Infection, Inflammation, Immunity, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomDouglas Miller4Translational Medicine Research Collaboration, Pfizer Research, Cambridge MA & Collegeville, PA, United StatesNeil Thomson1Respiratory Medicine; Infection, Inflammation, Immunity, University of Glasgow and Gartnavel General Hospital, Glasgow, United Kingdom
- Sputum matrix metalloproteinase-9 is associated with emphysema on computed tomography in COPDBy Rekha Chaudhuri, Charles McSharry, Jeffrey Brady, Christal Grierson, Claudia-Martina Messow, Mark Spears, Karl Nocka, William MacNee, Martin Connell, John Murchison, Michael Sproule, Douglas Miller and Neil C. ThomsonRekha Chaudhuri1Respiratory Medicine, Immunology, Radiology, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomCharles McSharry1Respiratory Medicine, Immunology, Radiology, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomJeffrey Brady2Translational Medicine Research Collaboration, Pfizer Research, Dundee, United KingdomChristal Grierson2Translational Medicine Research Collaboration, Pfizer Research, Dundee, United KingdomClaudia-Martina Messow3Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United KingdomMark Spears1Respiratory Medicine, Immunology, Radiology, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomKarl Nocka4Translational Medicine Research Collaboration, Pfizer Research, Cambridge MA & Collegeville, PA, United StatesWilliam MacNee5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomMartin Connell5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomJohn Murchison5MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United KingdomMichael Sproule1Respiratory Medicine, Immunology, Radiology, University of Glasgow and Gartnavel General Hospital, Glasgow, United KingdomDouglas Miller4Translational Medicine Research Collaboration, Pfizer Research, Cambridge MA & Collegeville, PA, United StatesNeil C. Thomson1Respiratory Medicine, Immunology, Radiology, University of Glasgow and Gartnavel General Hospital, Glasgow, United Kingdom
- Evaluation of the role of inflammation in chronic airways disease (ERICA): Midpoint evaluationBy Nichola Gale, Divya Mohan, Carmel McEniery, Charlotte Bolton, William MacNee, Jonathan Fuld, Ruth Tal-Singer, Dennis Shale, Cockcroft John, Polkey Mike and Wilkinson IanNichola Gale1Cardiorespiratory Medicine, Wales Heart Research Institute, Cardiff University, Cardiff, United KingdomDivya Mohan2NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, United KingdomCarmel McEniery3Clinical Pharmacology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, United KingdomCharlotte Bolton4Nottingham Respiratory Research Unit, Nottingham University, Nottingham, United KingdomWilliam MacNee5MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United KingdomJonathan Fuld6Department of Respiratory Medicine, University of Cambridge, Cambridge, United KingdomRuth Tal-Singer7Respiratory Therapy Area Unit, GlaxoSmithKline, King of Prussia, United StatesDennis Shale1Cardiorespiratory Medicine, Wales Heart Research Institute, Cardiff University, Cardiff, United KingdomCockcroft John1Cardiorespiratory Medicine, Wales Heart Research Institute, Cardiff University, Cardiff, United KingdomPolkey Mike2NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, United KingdomWilkinson Ian3Clinical Pharmacology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
- Characteristics, stability and outcomes of the gold 2011 copd groups in the eclipse cohortBy Alvar Agusti, Lisa D. Edwards, Bartolomé Celli, William MacNee, Peter M. A. Calverley, Hana Mullerova, David A. Lomas, Emiel Wouters, Per Bakke, Steve Rennard, Courtney Crim, Bruce E. Miller, Harvey O. Coxson, Julie C. Yates, Ruth Tal-Singer, Jørgen Vestbo and for the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators (see Appendix)Article | Published in 2013 in European Respiratory JournalAlvar Agusti*Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias, FISIB, Mallorca, SpainLisa D. Edwards#GlaxoSmithKline, Research Triangle Park, NC, USABartolomé Celli¶Dept of Respiratory Medicine; Brigham and Women's Hospital, Boston, MA, USAWilliam MacNee+University of Edinburgh & Royal Infirmary, Edinburgh, UKPeter M. A. Calverley§Dept of Respiratory Medicine; University Hospital Aintree, Liverpool, UKHana MullerovafEpidemiology, GlaxoSmithKline R&D, Stockley Park, Middlesex, UKDavid A. Lomas**Dept of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, UKEmiel Wouters##Dept of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, the NetherlandsPer Bakke¶¶Institute of Medicine, University of Bergen, and Dept of Thoracic Medicine, Haukeland University Hospital, Bergen, NorwaySteve Rennard++University of Nebraska Medical Center, Omaha, NE, USACourtney Crim#GlaxoSmithKline, Research Triangle Park, NC, USABruce E. Miller§§GlaxoSmithKline, King of Prussia, PA, USAHarvey O. CoxsonffDept of Radiology, University of British Columbia, Vancouver General Hospital, Vancouver, BC, CanadaJulie C. Yates#GlaxoSmithKline, Research Triangle Park, NC, USARuth Tal-Singer§§GlaxoSmithKline, King of Prussia, PA, USAJørgen Vestbo***Dept of Respiratory Medicine, Odense University Hospital/University of Southern Denmark, Denmark, and University of Manchester, Manchester Academic Health Sciences Centre, UK
- Validity of physical activity monitors during daily life in patients with COPDBy Roberto A Rabinovich, Zafeiris Louvaris, Yogini Raste, Daniel Langer, Hans Van Remoortel, Santiago Giavedoni, Chris Burtin, Eloisa M. G. Regueiro, Ioannis Vogiatzis, Nicholas S. Hopkinson, Michael I. Polkey, Frederick J. Wilson, William MacNee, Klaas R. Westerterp and Thierry TroostersArticle | Published in 2013 in European Respiratory JournalRoberto A Rabinovich*ELEGI Colt Laboratory, Centre for Inflammation Research. The Queen's Medical Research Institute, University of Edinburgh, Scotland, UK##These authors (RR and ZL) contributed equally to this workZafeiris Louvaris#Dept of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, National & Kapodistrian University of Athens, M' Simou and GP Livanos Laboratories, Thorax Foundation, Athens, Greece##These authors (RR and ZL) contributed equally to this workYogini Raste¶NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomDaniel Langer+Faculty of Kinesiology and Rehabilitation Sciences, Dept of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumHans Van Remoortel+Faculty of Kinesiology and Rehabilitation Sciences, Dept of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumSantiago Giavedoni*ELEGI Colt Laboratory, Centre for Inflammation Research. The Queen's Medical Research Institute, University of Edinburgh, Scotland, UKChris Burtin+Faculty of Kinesiology and Rehabilitation Sciences, Dept of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumEloisa M. G. Regueiro§Laboratory of Respiratory Physiotherapy, Universidade Federal de São Carlos - UFSCar, São Carlos, BrazilIoannis Vogiatzis#Dept of Critical Care Medicine, Pulmonary Rehabilitation Centre, Evangelismos Hospital, National & Kapodistrian University of Athens, M' Simou and GP Livanos Laboratories, Thorax Foundation, Athens, GreeceNicholas S. Hopkinson¶NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomMichael I. Polkey¶NIHR Respiratory Biomedical Research Unit of the Royal Brompton and Harefield NHS Foundation Trust and National Heart & Lung Institute, Imperial College London, London, United KingdomFrederick J. WilsonfPrecision Medicine, Pfizer Worldwide Research and Development, Sandwich, Kent, United KingdomWilliam MacNee*ELEGI Colt Laboratory, Centre for Inflammation Research. The Queen's Medical Research Institute, University of Edinburgh, Scotland, UKKlaas R. Westerterp**Dept of Human Biology, Maastricht University, Maastricht, the NetherlandsThierry Troosters+Faculty of Kinesiology and Rehabilitation Sciences, Dept of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
- Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthmaBy Rekha Chaudhuri, Charles McSharry, Jeffrey Brady, Christal Grierson, C. Martina Messow, Mark Spears, Gino Miele, Karl Nocka, William MacNee, Martin Connell, John T. Murchison, Michael Sproule, Omar J. Hilmi, Douglas K. Miller and Neil C. ThomsonArticle | Published in 2014 in European Respiratory JournalRekha Chaudhuri1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKCharles McSharry1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKJeffrey Brady2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKChristal Grierson2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKC. Martina Messow5Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UKMark Spears1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKGino Miele2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKKarl Nocka3Pfizer Research/Translational Medicine Research Collaboration, Cambridge MA, USAWilliam MacNee6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKMartin Connell6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKJohn T. Murchison6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKMichael Sproule7Radiology Dept, Gartnavel General Hospital, Glasgow, UKOmar J. Hilmi8Ear Nose and Throat Dept, Gartnavel General Hospital, Glasgow, UKDouglas K. Miller4Pfizer Research/Translational Medicine Research Collaboration, Collegeville, PA, USANeil C. Thomson1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK
- Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthmaBy Rekha Chaudhuri, Charles McSharry, Jeffrey Brady, Christal Grierson, C. Martina Messow, Mark Spears, Gino Miele, Karl Nocka, William MacNee, Martin Connell, John T. Murchison, Michael Sproule, Omar J. Hilmi, Douglas K. Miller and Neil C. ThomsonRekha Chaudhuri1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKCharles McSharry1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKJeffrey Brady2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKChristal Grierson2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKC. Martina Messow5Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UKMark Spears1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UKGino Miele2Pfizer Research/Translational Medicine Research Collaboration, Dundee, UKKarl Nocka3Pfizer Research/Translational Medicine Research Collaboration, Cambridge MA, USAWilliam MacNee6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKMartin Connell6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKJohn T. Murchison6University of Edinburgh/Medical Research Council Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, UKMichael Sproule7Radiology Dept, Gartnavel General Hospital, Glasgow, UKOmar J. Hilmi8Ear Nose and Throat Dept, Gartnavel General Hospital, Glasgow, UKDouglas K. Miller4Pfizer Research/Translational Medicine Research Collaboration, Collegeville, PA, USANeil C. Thomson1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK
- Ageing and the border between health and diseaseBy William MacNee, Roberto A. Rabinovich and Gourab ChoudhuryArticle | Published in 2014 in European Respiratory JournalWilliam MacNeeELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UKRoberto A. RabinovichELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UKGourab ChoudhuryELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK
- The PROactive innovative conceptual framework on physical activityBy Fabienne Dobbels, Corina de Jong, Ellen Drost, Janneke Elberse, Chryssoula Feridou, Laura Jacobs, Roberto Rabinovich, Anja Frei, Milo A. Puhan, Willem I. de Boer, Thys van der Molen, Kate Williams, Hillary Pinnock, Thierry Troosters, Niklas Karlsson, Karoly Kulich, Katja Rüdell and the PROactive consortiumFabienne Dobbels1Health Services and Nursing Research, University of Leuven, Leuven, BelgiumCorina de Jong2Dept of General Practice, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands13These authors equally contributedEllen Drost3ELEGI Laboratory, Center for Inflammation Research, University of Edinburgh, Edinburgh, UK13These authors equally contributedJanneke Elberse4Lung Foundation Netherlands, Amersfoort, The Netherlands13These authors equally contributedChryssoula Feridou5Dept of Critical Care Medicine and Pulmonary Services, Thorax Foundation, Athens, Greece13These authors equally contributedLaura Jacobs1Health Services and Nursing Research, University of Leuven, Leuven, Belgium13These authors equally contributedRoberto Rabinovich3ELEGI Laboratory, Center for Inflammation Research, University of Edinburgh, Edinburgh, UKAnja Frei6Horten Centre and Institute of Social and Preventive Medicine, University of Zurich, Zurich, SwitzerlandMilo A. Puhan6Horten Centre and Institute of Social and Preventive Medicine, University of Zurich, Zurich, SwitzerlandWillem I. de Boer4Lung Foundation Netherlands, Amersfoort, The NetherlandsThys van der Molen2Dept of General Practice, University Medical Center Groningen, University of Groningen, Groningen, The NetherlandsKate Williams7Outcomes and Evidence, Global Health and Value, Pfizer, Walton Oaks, UKHillary Pinnock8Allergy and Respiratory Research Group, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UKThierry Troosters9Dept of Rehabilitation Sciences, University of Leuven, Leuven, BelgiumNiklas Karlsson10AstraZeneca, Research and Development, Health Economics and Outcomes Research, Medical Science, Mölndal, SwedenKaroly Kulich11Patient Reported Outcomes Division, Novartis, Basel, SwitzerlandKatja Rüdell7Outcomes and Evidence, Global Health and Value, Pfizer, Walton Oaks, UK12For a list of the PROactive consortium members see the Acknowledgements section
- Ageing and the border between health and diseaseBy William MacNee, Roberto A. Rabinovich and Gourab ChoudhuryWilliam MacNeeELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UKRoberto A. RabinovichELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UKGourab ChoudhuryELEGI Colt Research Laboratories, MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK
- One-year change in health status and outcomes in chronic obstructive pulmonary diseaseBy Sarah Wilke, Paul Jones, Hana Müllerova, Nicholas Locantore, Jorgen Vestbo, Ruth Tal-Singer, Frits Franssen, Alvar Agusti, Per Bakke, Peter Calverley, Harvey Coxson, Courtney Crim, Lisa Edwards, David Lomas, William MacNee, Stephan Rennard, Julie Yates, Emiel Wouters and Martijn SpruitSarah Wilke1Department of Research & Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, NetherlandsPaul Jones2Division of Clinical Science, St. George’s University of London, London, United KingdomHana Müllerova3Respiratory Epidemiology, GlaxoSmithKline, Uxbridge, United KingdomNicholas Locantore4GlaxoSmithKline, Research Triangle Park, North Carolina,Jorgen Vestbo5Department of Respiratory Medicine, Odense University Hospital, Clinical Institute, University of Southern Denmark, Odense, Denmark6Respiratory Research Group, Manchester Academic Health Sciences Centre, University Hospital South Manchester NHS Foundation, Manchester, United KingdomRuth Tal-Singer7GlaxoSmithKline, GlaxoSmithKline Research and Development, King of Prussia,Frits Franssen1Department of Research & Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, NetherlandsAlvar Agusti8Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias (CIBERES), Barcelona, SpainPer Bakke9Department of Thoracic Medicine, Institute of Clinical Science, University of Bergen, Haukeland University Hospital, Bergen, NorwayPeter Calverley10Division of Infection and Immunity Clinical Sciences Centre, University Hospital Aintree, Liverpool, United KingdomHarvey Coxson11Department of Radiology, Vancouver General Hospital, University of British Columbia, Vancover, CanadaCourtney Crim4GlaxoSmithKline, Research Triangle Park, North Carolina,Lisa Edwards4GlaxoSmithKline, Research Triangle Park, North Carolina,David Lomas12University of Cambridge, Cambridge Institute for Medical Research, Department of Medicine, Cambridge, United KingdomWilliam MacNee13MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United KingdomStephan Rennard14Department of Pulmonary and Critical Care Medicine, University of Nebraska Medical Center, Omaha,Julie Yates4GlaxoSmithKline, Research Triangle Park, North Carolina,Emiel Wouters1Department of Research & Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, Netherlands15Department of Respiratory Medicine, Maastricht University Medical Centre+, Maastricht, NetherlandsMartijn Spruit1Department of Research & Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, Netherlands
- 18F-fluorodeoxyglucose (18FDG) PET pulmonary imaging:comparative methodology in COPD patientsBy Gourab Choudhury, Alison Fletcher, Martin Connell, Tim Clark, Susie Ferguson, Roberto Rabinovich, Nick Weir, Brandon Whitcher, Iain Kilty, William Vennart, Edwin J.R. van Beek and William MacNeeGourab Choudhury1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomAlison Fletcher2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomMartin Connell2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomTim Clark2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomSusie Ferguson1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomRoberto Rabinovich1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomNick Weir2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomBrandon Whitcher3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, MA,Iain Kilty3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, MA,William Vennart3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, MA,Edwin J.R. van Beek2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomWilliam MacNee1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United Kingdom
- Circulating desmosine relates to cardiovascular comorbidity, coronary artery calcification score (CACS), systemic inflammation and mortality in patients with COPDBy Roberto Rabinovich, Bruce Millar, Karolina Wrobel, Gourag Chaudhury, Kareshma Ranjit, Ellen Drost, Lisa Edwards, David Lomas, Stephen Rennard, Alvar Agusti, Ruth Tal-Singer, Jørgen Vestbo, Emiel Wouters, Edwin J.R. Van Beek, John Murchison, William MacNee and Jeffrey HuangRoberto Rabinovich1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomBruce Millar3GlaxoSmithKline R&D, King of Prussia, GlsxoSmithKline, Pennsylvania,Karolina Wrobel2Medical Research Institute, School of Medicine, The University of Dundee, Dundee, Scotland, United KingdomGourag Chaudhury1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomKareshma Ranjit1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomEllen Drost1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomLisa Edwards4GlaxoSmithKline, Research Triangle Park, GlsxoSmithKline, NC,David Lomas5Faculty of Medical Sciences, University College London, London, United KingdomStephen Rennard6Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska, Omaha,Alvar Agusti7Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias, FISIB, Universitat de Barclona, Barcelona, SpainRuth Tal-Singer3GlaxoSmithKline R&D, King of Prussia, GlsxoSmithKline, Pennsylvania,Jørgen Vestbo8Department of Respiratory Medicine, Odense University & University of Southern Denmark, Odense, DenmarkEmiel Wouters9Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, NetherlandsEdwin J.R. Van Beek10Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomJohn Murchison11Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, United KingdomWilliam MacNee1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomJeffrey Huang2Medical Research Institute, School of Medicine, The University of Dundee, Dundee, Scotland, United Kingdom
- Measurement of cardiac troponin identifies patients with moderate to large pulmonary emboli and right ventricular strainBy Jack Andrews, William MacNee and John MurchisonJack Andrews1Respiratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, United KingdomWilliam MacNee1Respiratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, United KingdomJohn Murchison2Clinical Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
- HELP-COPD: A qualitative study of need in people with severe COPDBy Hilary Pinnock, Marilyn Kendall, Susan Buckingham, Susie Ferguson, Aziz Sheikh, William MacNee, Patrick White, Allison Worth, Kirsty Boyd and Scott MurrayHilary Pinnock1Allergy and Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomMarilyn Kendall1Allergy and Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomSusan Buckingham1Allergy and Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomSusie Ferguson2Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United KingdomAziz Sheikh1Allergy and Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomWilliam MacNee2Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United KingdomPatrick White3Department of Primary Care and Public Health Sciences, King’s College London, London, United KingdomAllison Worth4Wellcome Trust Clinical Research Facility, The University of Edinburgh, Edinburgh, United KingdomKirsty Boyd5Primary Palliative Care Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United KingdomScott Murray5Primary Palliative Care Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United Kingdom
- Premature aging and skeletal muscle dysfunction in COPD patients: Development of a cell culture modelBy Lakhdar Ramzi, Choudhury Gourab, Jennifer McLeish, Elen Drost, Liane McGlynn, Paul Shiels, William MacNee and Roberto RabinovichLakhdar Ramzi1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomChoudhury Gourab1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomJennifer McLeish1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomElen Drost1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomLiane McGlynn2College of Medical, Veterinary & Life Sciences Institute of Cancer Sciences, The University of Glasgow, Glasgow, Scotland, United KingdomPaul Shiels2College of Medical, Veterinary & Life Sciences Institute of Cancer Sciences, The University of Glasgow, Glasgow, Scotland, United KingdomWilliam MacNee1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomRoberto Rabinovich1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
- Telomere attrition in circulating white blood cells in COPD relates to lung function and outcomesBy Roberto Rabinovich, Gourab Choudhuri, Ramzi Lakhdar, Ellen Drost, Liane McGlynn, Jing Bai, Paul Shiels, Bruce Millar, Ruth Tal-Singer, Alvar Agusti and William MacNeeRoberto Rabinovich1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomGourab Choudhuri1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomRamzi Lakhdar1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomEllen Drost1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomLiane McGlynn2College of Medical, Veterinary & Life Sciences Institute of Cancer Sciences, The University of Glasgow, Glasgow, Scotland, United KingdomJing Bai1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United KingdomPaul Shiels2College of Medical, Veterinary & Life Sciences Institute of Cancer Sciences, The University of Glasgow, Glasgow, Scotland, United KingdomBruce Millar3GlaxoSmithKline R&D, King of Prusia, GlsxoSmithKline, Pennsylvania,Ruth Tal-Singer3GlaxoSmithKline R&D, King of Prusia, GlsxoSmithKline, Pennsylvania,Alvar Agusti4Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias, FISIB, Universitat de Barcelona, Barcelona, SpainWilliam MacNee1ELEGI/Colt Laboratory. Centre for Inflammation Research. The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
- An official American Thoracic Society/European Respiratory Society statement: research questions in COPDBy Bartolome R. Celli, Marc Decramer, Jadwiga A. Wedzicha, Kevin C. Wilson, Alvar Agustí, Gerard J. Criner, William MacNee, Barry J. Make, Stephen I. Rennard, Robert A. Stockley, Claus Vogelmeier, Antonio Anzueto, David H. Au, Peter J. Barnes, Pierre-Regis Burgel, Peter M. Calverley, Ciro Casanova, Enrico M. Clini, Christopher B. Cooper, Harvey O. Coxson, Daniel J. Dusser, Leonardo M. Fabbri, Bonnie Fahy, Gary T. Ferguson, Andrew Fisher, Monica J. Fletcher, Maurice Hayot, John R. Hurst, Paul W. Jones, Donald A. Mahler, François Maltais, David M. Mannino, Fernando J. Martinez, Marc Miravitlles, Paula M. Meek, Alberto Papi, Klaus F. Rabe, Nicolas Roche, Frank C. Sciurba, Sanjay Sethi, Nikos Siafakas, Don D. Sin, Joan B. Soriano, James K. Stoller, Donald P. Tashkin, Thierry Troosters, Geert M. Verleden, Johny Verschakelen, Jorgen Vestbo, John W. Walsh, George R. Washko, Robert A. Wise, Emiel F.M. Wouters and Richard L. ZuWallackBartolome R. CelliFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsMarc DecramerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJadwiga A. WedzichaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsKevin C. WilsonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsAlvar AgustíFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsGerard J. CrinerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsWilliam MacNeeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsBarry J. MakeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsStephen I. RennardFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsRobert A. StockleyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsClaus VogelmeierFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsAntonio AnzuetoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDavid H. AuFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsPeter J. BarnesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsPierre-Regis BurgelFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsPeter M. CalverleyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsCiro CasanovaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsEnrico M. CliniFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsChristopher B. CooperFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsHarvey O. CoxsonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDaniel J. DusserFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsLeonardo M. FabbriFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsBonnie FahyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsGary T. FergusonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsAndrew FisherFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsMonica J. FletcherFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsMaurice HayotFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJohn R. HurstFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsPaul W. JonesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDonald A. MahlerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsFrançois MaltaisFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDavid M. ManninoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsFernando J. MartinezFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsMarc MiravitllesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsPaula M. MeekFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsAlberto PapiFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsKlaus F. RabeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsNicolas RocheFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsFrank C. SciurbaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsSanjay SethiFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsNikos SiafakasFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDon D. SinFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJoan B. SorianoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJames K. StollerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsDonald P. TashkinFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsThierry TroostersFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsGeert M. VerledenFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJohny VerschakelenFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJorgen VestboFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsJohn W. WalshFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsGeorge R. WashkoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsRobert A. WiseFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsEmiel F.M. WoutersFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authorsRichard L. ZuWallackFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section. 1Project co-chairs; should be considered co-first authors
- An official American Thoracic Society/European Respiratory Society statement: research questions in COPDBy Bartolome R. Celli, Marc Decramer, Jadwiga A. Wedzicha, Kevin C. Wilson, Alvar A. Agustí, Gerard J. Criner, William MacNee, Barry J. Make, Stephen I. Rennard, Robert A. Stockley, Claus Vogelmeier, Antonio Anzueto, David H. Au, Peter J. Barnes, Pierre-Regis Burgel, Peter M. Calverley, Ciro Casanova, Enrico M. Clini, Christopher B. Cooper, Harvey O. Coxson, Daniel J. Dusser, Leonardo M. Fabbri, Bonnie Fahy, Gary T. Ferguson, Andrew Fisher, Monica J. Fletcher, Maurice Hayot, John R. Hurst, Paul W. Jones, Donald A. Mahler, François Maltais, David M. Mannino, Fernando J. Martinez, Marc Miravitlles, Paula M. Meek, Alberto Papi, Klaus F. Rabe, Nicolas Roche, Frank C. Sciurba, Sanjay Sethi, Nikos Siafakas, Don D. Sin, Joan B. Soriano, James K. Stoller, Donald P. Tashkin, Thierry Troosters, Geert M. Verleden, Johny Verschakelen, Jorgen Vestbo, John W. Walsh, George R. Washko, Robert A. Wise, Emiel F.M. Wouters and Richard L. ZuWallackBartolome R. CelliFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionMarc DecramerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJadwiga A. WedzichaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionKevin C. WilsonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionAlvar A. AgustíFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionGerard J. CrinerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionWilliam MacNeeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionBarry J. MakeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionStephen I. RennardFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionRobert A. StockleyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionClaus VogelmeierFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionAntonio AnzuetoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDavid H. AuFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionPeter J. BarnesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionPierre-Regis BurgelFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionPeter M. CalverleyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionCiro CasanovaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionEnrico M. CliniFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionChristopher B. CooperFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionHarvey O. CoxsonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDaniel J. DusserFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionLeonardo M. FabbriFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionBonnie FahyFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionGary T. FergusonFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionAndrew FisherFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionMonica J. FletcherFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionMaurice HayotFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJohn R. HurstFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionPaul W. JonesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDonald A. MahlerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionFrançois MaltaisFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDavid M. ManninoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionFernando J. MartinezFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionMarc MiravitllesFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionPaula M. MeekFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionAlberto PapiFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionKlaus F. RabeFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionNicolas RocheFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionFrank C. SciurbaFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionSanjay SethiFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionNikos SiafakasFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDon D. SinFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJoan B. SorianoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJames K. StollerFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionDonald P. TashkinFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionThierry TroostersFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionGeert M. VerledenFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJohny VerschakelenFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJorgen VestboFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionJohn W. WalshFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionGeorge R. WashkoFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionRobert A. WiseFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionEmiel F.M. WoutersFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements sectionRichard L. ZuWallackFurther details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section
- Clinical and prognostic heterogeneity of C and D GOLD groupsBy Alvar Agustí, Stephen Rennard, Lisa D. Edwards, William MacNee, Emiel Wouters, Bruce Miller, Ruth Tal-Singer, Hana Mullerova and Bartolomé CelliAlvar Agustí1Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona and CIBER Enfermedades Respiratorias (CIBERES), Barcelona, SpainStephen Rennard2Dept of Pulmonary and Critical Care Medicine, University of Nebraska Medical Center, Omaha, NE, USALisa D. Edwards3Clinical Statistics, GlaxoSmithKline R&D, Research Triangle Park, NC, USAWilliam MacNee4ELEGI Labs, University of Edinburgh, Edinburgh, UKEmiel Wouters5Dept of Respiratory Medicine, Maastricht University Medical Center, Maastricht, The NetherlandsBruce Miller6Respiratory Therapy Area Unit, GlaxoSmithKline R&D, King of Prussia, PA, USARuth Tal-Singer6Respiratory Therapy Area Unit, GlaxoSmithKline R&D, King of Prussia, PA, USAHana Mullerova7Worldwide Epidemiology, GlaxoSmithKline R&D, Uxbridge, EnglandBartolomé Celli8Dept of Respiratory Medicine, Brigham and Women's Hospital, Boston, MA, USA
- Continuous fat-free mass decline in COPD: fact or fiction?By Erica P.A. Rutten, Martijn A. Spruit, Merry-Lynn N. McDonald, Stephan Rennard, Alvar Agusti, Bartolome Celli, Bruce E. Miller, Courtney Crim, Peter M.A. Calverley, Corrine Hanson, William MacNee, Frits M.E. Franssen, Lowie Vanfleteren and Emiel F.M. WoutersArticle | Published in 2015 in European Respiratory JournalErica P.A. Rutten1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The NetherlandsMartijn A. Spruit1Dept of Research and Education, CIRO, Horn, The Netherlands3REVAL – Rehabilitation Research Center, BIOMED – Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, BelgiumMerry-Lynn N. McDonald4Channing Division of Network Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USAStephan Rennard5Division of Internal Medicine, University of Nebraska, Nebraska Medical Center, Omaha, USAAlvar Agusti6Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain7CIBERES, Madrid, SpainBartolome Celli8Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USABruce E. Miller9GlaxoSmithKline, King of Prussia, PA, USACourtney Crim10GlaxoSmithKline, Research Triangle Park, NC, USAPeter M.A. Calverley11The University of Liverpool, Liverpool, UKCorrine Hanson12Medical Nutrition Education, University of Nebraska, Nebraska Medical Center, Omaha, USAWilliam MacNee13The University of Edinburgh, Edinburgh, UKFrits M.E. Franssen1Dept of Research and Education, CIRO, Horn, The NetherlandsLowie Vanfleteren1Dept of Research and Education, CIRO, Horn, The NetherlandsEmiel F.M. Wouters1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The Netherlands
- Continuous fat-free mass decline in COPD: fact or fiction?By Erica P.A. Rutten, Martijn A. Spruit, Merry-Lynn N. McDonald, Stephen Rennard, Alvar Agusti, Bartolome Celli, Bruce E. Miller, Courtney Crim, Peter M.A. Calverley, Corrine Hanson, William MacNee, Frits M.E. Franssen, Lowie Vanfleteren and Emiel F.M. WoutersArticle | Published in 2015 in European Respiratory JournalErica P.A. Rutten1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The NetherlandsMartijn A. Spruit1Dept of Research and Education, CIRO, Horn, The Netherlands3REVAL – Rehabilitation Research Center, BIOMED – Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, BelgiumMerry-Lynn N. McDonald4Channing Division of Network Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USAStephen Rennard5Division of Internal Medicine, University of Nebraska, Nebraska Medical Center, Omaha, USAAlvar Agusti6Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain7CIBERES, Madrid, SpainBartolome Celli8Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USABruce E. Miller9GlaxoSmithKline, King of Prussia, PA, USACourtney Crim10GlaxoSmithKline, Research Triangle Park, NC, USAPeter M.A. Calverley11The University of Liverpool, Liverpool, UKCorrine Hanson12Medical Nutrition Education, University of Nebraska, Nebraska Medical Center, Omaha, USAWilliam MacNee13The University of Edinburgh, Edinburgh, UKFrits M.E. Franssen1Dept of Research and Education, CIRO, Horn, The NetherlandsLowie Vanfleteren1Dept of Research and Education, CIRO, Horn, The NetherlandsEmiel F.M. Wouters1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The Netherlands
- Continuous fat-free mass decline in COPD: fact or fiction?By Erica P.A. Rutten, Martijn A. Spruit, Merry-Lynn N. McDonald, Stephen Rennard, Alvar Agusti, Bartolome Celli, Bruce E. Miller, Courtney Crim, Peter M.A. Calverley, Corrine Hanson, William MacNee, Frits M.E. Franssen, Lowie Vanfleteren and Emiel F.M. WoutersErica P.A. Rutten1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The NetherlandsMartijn A. Spruit1Dept of Research and Education, CIRO, Horn, The Netherlands3REVAL – Rehabilitation Research Center, BIOMED – Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, BelgiumMerry-Lynn N. McDonald4Channing Division of Network Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USAStephen Rennard5Division of Internal Medicine, University of Nebraska, Nebraska Medical Center, Omaha, NE, USAAlvar Agusti6Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain7CIBERES, Madrid, SpainBartolome Celli8Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USABruce E. Miller9GlaxoSmithKline, King of Prussia, PA, USACourtney Crim10GlaxoSmithKline, Research Triangle Park, NC, USAPeter M.A. Calverley11The University of Liverpool, Liverpool, UKCorrine Hanson12Medical Nutrition Education, University of Nebraska, Nebraska Medical Center, Omaha, NE, USAWilliam MacNee13The University of Edinburgh, Edinburgh, UKFrits M.E. Franssen1Dept of Research and Education, CIRO, Horn, The NetherlandsLowie Vanfleteren1Dept of Research and Education, CIRO, Horn, The NetherlandsEmiel F.M. Wouters1Dept of Research and Education, CIRO, Horn, The Netherlands2Maastricht University Medical Center, Maastricht, The Netherlands
- Markers of ageing in the limb muscle of patients with COPDBy Ramzi Lakhdar, Ellen Drost, Paul G. Shiels, William MacNee and Roberto RabinovichRamzi Lakhdar1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomEllen Drost1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomPaul G. Shiels2University of Glasgow, College of Medical, Veterinary & Life Sciences Institute of Cancer Sciences, Glasgow, United KingdomWilliam MacNee1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomRoberto Rabinovich1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United Kingdom
- Validation of five non-invasive respiratory rate monitors in patients with COPD in a laboratory settingBy Noah Rubio, Richard Parker, Hilary Pinnock, Christopher Weir, Janet Hanley, Lucy McClougham, William MacNee, Brian McKinstry and Roberto RabinovichNoah Rubio1Edinburgh Lung and the Environment Group Initiative, University of Edinburgh, Edinburgh, United KingdomRichard Parker2Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomHilary Pinnock2Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomChristopher Weir2Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomJanet Hanley3School of Nursing (Midwifery and Social Care ), Edinburgh Napier University, Edinburgh, United KingdomLucy McClougham2Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomWilliam MacNee1Edinburgh Lung and the Environment Group Initiative, University of Edinburgh, Edinburgh, United KingdomBrian McKinstry2Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United KingdomRoberto Rabinovich1Edinburgh Lung and the Environment Group Initiative, University of Edinburgh, Edinburgh, United Kingdom
- Apoptosis in vastus lateralis muscle of patients with COPDBy Ramzi Lakhdar, Ellen Drost, William MacNee and Roberto RabinovichRamzi LakhdarEdinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomEllen DrostEdinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomWilliam MacNeeEdinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United KingdomRoberto RabinovichEdinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens Medical Research Institute, Edinburgh, United Kingdom
- 18F-Fluorodeoxyglucose (18FDG) PET pulmonary imaging: Role in detecting vascular inflammationBy Janice Wong, Alex Vesey, Susie Ferguson, Alison Fletcher, Tim Clark, Martin Connell, Brandon Whitcher, Iain Kilty, William Vennart, Edwin J.R. Van Beek, William MacNee and Gourab ChoudhuryJanice Wong1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomAlex Vesey2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomSusie Ferguson1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomAlison Fletcher2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomTim Clark2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomMartin Connell2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomBrandon Whitcher3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, United StatesIain Kilty3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, United StatesWilliam Vennart3Pfizer Worldwide Research & Development, Pfizer Worldwide Research & Development, Cambridge, United StatesEdwin J.R. Van Beek2Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, United KingdomWilliam MacNee1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United KingdomGourab Choudhury1Centre for Research and Inflammation, Queens Medical Research Institute, Edinburgh, United Kingdom
- Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPDBy Roberto A. Rabinovich, Bruce E. Miller, Karolina Wrobel, Kareshma Ranjit, Michelle C. Williams, Ellen Drost, Lisa D. Edwards, David A. Lomas, Stephen I. Rennard, Alvar Agustí, Ruth Tal-Singer, Jørgen Vestbo, Emiel F.M. Wouters, Michelle John, Edwin J.R. van Beek, John T Murchison, Charlotte E Bolton, William MacNee and Jeffrey T.J. HuangArticle | Published in 2016 in European Respiratory JournalRoberto A. Rabinovich1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKBruce E. Miller2Respiratory Therapy Area Unit, GSK, King of Prussia, PA, USAKarolina Wrobel3Medical Research Institute, School of Medicine, University of Dundee, Dundee, UKKareshma Ranjit1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKMichelle C. Williams4University/BHF Centre for Cardiovascular Science, Edinburgh, UKEllen Drost1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKLisa D. Edwards5PAREXEL International, Durham, NC, USADavid A. Lomas6Faculty of Medical Sciences, University College London, London, UKStephen I. Rennard7Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska, Omaha, NE, USA8Clinical Discovery Unit, AstraZeneca, Cambridge, UKAlvar Agustí9Servei de Pneumologia, Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias (CIBERES), Barcelona, SpainRuth Tal-Singer2Respiratory Therapy Area Unit, GSK, King of Prussia, PA, USAJørgen Vestbo10Centre for Respiratory Medicine and Allergy, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UKEmiel F.M. Wouters11Dept of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The NetherlandsMichelle John12Nottingham Respiratory Research Unit, School of Medicine, University of Nottingham, Nottingham, UKEdwin J.R. van Beek13Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, UKJohn T Murchison14Dept of Radiology, Royal Infirmary of Edinburgh, UKCharlotte E Bolton12Nottingham Respiratory Research Unit, School of Medicine, University of Nottingham, Nottingham, UKWilliam MacNee1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKJeffrey T.J. Huang3Medical Research Institute, School of Medicine, University of Dundee, Dundee, UK
- Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPDBy Roberto A. Rabinovich, Bruce E. Miller, Karolina Wrobel, Kareshma Ranjit, Michelle C. Williams, Ellen Drost, Lisa D. Edwards, David A. Lomas, Stephen I. Rennard, Alvar Agustí, Ruth Tal-Singer, Jørgen Vestbo, Emiel F.M. Wouters, Michelle John, Edwin J.R. van Beek, John T Murchison, Charlotte E Bolton, William MacNee and Jeffrey T.J. HuangRoberto A. Rabinovich1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKBruce E. Miller2Respiratory Therapy Area Unit, GSK, King of Prussia, PA, USAKarolina Wrobel3Medical Research Institute, School of Medicine, University of Dundee, Dundee, UKKareshma Ranjit1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKMichelle C. Williams4University/BHF Centre for Cardiovascular Science, Edinburgh, UKEllen Drost1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKLisa D. Edwards5PAREXEL International, Durham, NC, USADavid A. Lomas6Faculty of Medical Sciences, University College London, London, UKStephen I. Rennard7Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska, Omaha, NE, USA8Clinical Discovery Unit, AstraZeneca, Cambridge, UKAlvar Agustí9Servei de Pneumologia, Thorax Institute, Hospital Clinic, IDIBAPS, Universitat de Barcelona and CIBER Enfermedades Respiratorias (CIBERES), Barcelona, SpainRuth Tal-Singer2Respiratory Therapy Area Unit, GSK, King of Prussia, PA, USAJørgen Vestbo10Centre for Respiratory Medicine and Allergy, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UKEmiel F.M. Wouters11Dept of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The NetherlandsMichelle John12Nottingham Respiratory Research Unit, School of Medicine, University of Nottingham, Nottingham, UKEdwin J.R. van Beek13Clinical Research Imaging Centre, Queens Medical Research Institute, Edinburgh, UKJohn T Murchison14Dept of Radiology, Royal Infirmary of Edinburgh, UKCharlotte E Bolton12Nottingham Respiratory Research Unit, School of Medicine, University of Nottingham, Nottingham, UKWilliam MacNee1Edinburgh Lung and the Environment Group Initiative (ELEGI), Centre for Inflammation and Research, Queens' Medical Research Institute, Edinburgh, UKJeffrey T.J. Huang3Medical Research Institute, School of Medicine, University of Dundee, Dundee, UK
- Interventions to modify physical activity in patients with COPD: a systematic reviewBy Leandro Cruz Mantoani, Noah Rubio, Brian McKinstry, William MacNee and Roberto A. RabinovichArticle | Published in 2016 in European Respiratory JournalLeandro Cruz Mantoani1ELEGI and COLT Laboratories, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UKNoah Rubio1ELEGI and COLT Laboratories, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UKBrian McKinstry2Edinburgh Health Services Research Unit/Edinburgh Clinical Trials Unit, Western General Hospital, Edinburgh, UK3Telescot Research Programme, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UKWilliam MacNee1ELEGI and COLT Laboratories, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UKRoberto A. Rabinovich1ELEGI and COLT Laboratories, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK
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