Laurie Lau
- Late-breaking abstract: Repeated bronchoconstriction without additional inflammation is sufficient to induce airway remodelling in asthmaBy Christopher Grainge, Jonathan Ward, Gemma Lahiff, Valdeep Dulay, Laurie Lau, Donna Davies and Peter HowarthChristopher GraingeDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomJonathan WardDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomGemma LahiffDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomValdeep DulayDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomLaurie LauDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomDonna DaviesDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United KingdomPeter HowarthDivision of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United Kingdom
- A low total sputum cell count is a marker for asthma remission during adolescenceBy Khalid Bawakid, Zamil Al-Shammari, Laurie Lau, Wilfried Karmaus, Susan Ewart, Ramesh Kurukulaaratchy, Graham Roberts, Abid Raza and Hasan ArshadKhalid Bawakid1Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, and David Hide Asthma and Allergy Research Unit, Isle of Wight, University of Southampton, United KingdomZamil Al-Shammari1Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, and David Hide Asthma and Allergy Research Unit, Isle of Wight, University of Southampton, United KingdomLaurie Lau2Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, University of Southampton, United KingdomWilfried Karmaus3Department of Epidemiology and Biostatistics, University of South Carolina, SC, United StatesSusan Ewart4Veterinary Medicine,, Michigan State University, East Lansing, MI, United StatesRamesh Kurukulaaratchy1Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, and David Hide Asthma and Allergy Research Unit, Isle of Wight, University of Southampton, United KingdomGraham Roberts1Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, and David Hide Asthma and Allergy Research Unit, Isle of Wight, University of Southampton, United KingdomAbid Raza2Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, University of Southampton, United KingdomHasan Arshad1Clinical and Experimental Academic Unit, Respiratory Biomedical Research Unit, and David Hide Asthma and Allergy Research Unit, Isle of Wight, University of Southampton, United Kingdom
- IL-5 and IL-13 are predictors of asthma remission; results from a birth cohortBy Daniel Neville, Vereesh Patil, Laurie Lau, Ramesh Kurukulaaratchy and Hasan ArshadDaniel Neville1Asthma and Allergy Research Centre, University of Southampton, Southampton, United KingdomVereesh Patil1Asthma and Allergy Research Centre, University of Southampton, Southampton, United KingdomLaurie Lau1Asthma and Allergy Research Centre, University of Southampton, Southampton, United KingdomRamesh Kurukulaaratchy1Asthma and Allergy Research Centre, University of Southampton, Southampton, United KingdomHasan Arshad1Asthma and Allergy Research Centre, University of Southampton, Southampton, United Kingdom
- Sputum neutrophil differential cell count in health and relationship to disease severity in asthmaBy Clair Barber, Scott Elliott, Jon Ward, Laurie Lau, Kerry Gove, Tom Brown, Hitasha Rupani, Tim Hinks, Ratko Djukanovic, Ramesh Kurukuaaratchy, Anoop Chauhan and Peter HowarthClair Barber1NIHR Respiratory BioMedical Research Unit, University Hospital Southampton, Southampton, Hampshire, United KingdomScott Elliott3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire, United KingdomJon Ward2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomLaurie Lau2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomKerry Gove2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomTom Brown3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire, United KingdomHitasha Rupani2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomTim Hinks2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomRatko Djukanovic2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United KingdomRamesh Kurukuaaratchy4Respiratory Medicine, University Hospital Southampton MHS Foundation Trust, Southampton, Hampshire, United KingdomAnoop Chauhan3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire, United KingdomPeter Howarth2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire, United Kingdom
- Late-breaking abstract: Surfactant protein D is dysregulated in severe asthmaBy Rose-Marie Mackay, Christopher Grainge, Laurie Lau, Clair Barber, Howard Clark and Peter HowarthRose-Marie Mackay1Clinical and Experimental Sciences, Faculty of Medicine, The University of Southampton, Southampton, Hampshire, United KingdomChristopher Grainge2Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, AustraliaLaurie Lau1Clinical and Experimental Sciences, Faculty of Medicine, The University of Southampton, Southampton, Hampshire, United KingdomClair Barber1Clinical and Experimental Sciences, Faculty of Medicine, The University of Southampton, Southampton, Hampshire, United KingdomHoward Clark1Clinical and Experimental Sciences, Faculty of Medicine, The University of Southampton, Southampton, Hampshire, United KingdomPeter Howarth1Clinical and Experimental Sciences, Faculty of Medicine, The University of Southampton, Southampton, Hampshire, United Kingdom
- LSC 2014 abstract - Targeting of microRNAs can restore innate anti-viral response in asthmaBy Hitasha Rupani, Patrick Dennison, Nivenka Jayasekera, Laurie Lau, Tilman Sanchez-Elsner and Peter HowarthHitasha Rupani1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United KingdomPatrick Dennison1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United KingdomNivenka Jayasekera1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United KingdomLaurie Lau1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United KingdomTilman Sanchez-Elsner1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United KingdomPeter Howarth1Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom
- Serum periostin in asthma: A potential biomarker for stratification in severe treatment-resistant asthmaBy Hitasha Rupani, Laurie Lau, Junya Ono, Shoichiro Ohta, Clair Barber, Scott Elliot, Tom Brown, Ramesh Kurukulaaratchy, Anoop Chauhan, Kenji Izuhara and Peter HowarthHitasha Rupani1Clinical and Experimental Sciences, University of Southampton, Southampton, Hampshire, United KingdomLaurie Lau1Clinical and Experimental Sciences, University of Southampton, Southampton, Hampshire, United KingdomJunya Ono2Shino-Test Corporation, Shino-Test Corporation, Kanagawa, JapanShoichiro Ohta3Department of Laboratory Medicine, Saga Medical School, Saga, JapanClair Barber4National Institute of Health Research Respiratory BioMedical Research Unit, Southampton General Hospital, Southampton, Hampshire, United KingdomScott Elliot5Respiratory Medicine, Portsmouth Hospital NHS Trust, Portsmouth, Hampshire, United KingdomTom Brown5Respiratory Medicine, Portsmouth Hospital NHS Trust, Portsmouth, Hampshire, United KingdomRamesh Kurukulaaratchy6Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, United KingdomAnoop Chauhan5Respiratory Medicine, Portsmouth Hospital NHS Trust, Portsmouth, Hampshire, United KingdomKenji Izuhara3Department of Laboratory Medicine, Saga Medical School, Saga, JapanPeter Howarth1Clinical and Experimental Sciences, University of Southampton, Southampton, Hampshire, United Kingdom
- Dissociation between clinical trial inclusion and exclusion criteria for trials in severe asthma and the reality of the patient populationBy Tom Brown, Hitasha Rupani, Clair Barber, Scott Elliot, Kerry Gove, Laurie Lau, Lorraine Hewitt, Emma Ray, Elisabeth Aitken, Sumita Kerley, Ramesh Kurukulaaratchy, Christopher Grainge, Ratko Djukanovic, Anoop Chauhan and Peter HowarthTom Brown1Respiratory Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, Hampshire, United KingdomHitasha Rupani2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United KingdomClair Barber3National Institute of Health Research UK Respiratory Bioscience Research Unit, Southampton General Hospital, Southampton, Hampshire, United KingdomScott Elliot1Respiratory Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, Hampshire, United KingdomKerry Gove2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United KingdomLaurie Lau2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United KingdomLorraine Hewitt3National Institute of Health Research UK Respiratory Bioscience Research Unit, Southampton General Hospital, Southampton, Hampshire, United KingdomEmma Ray3National Institute of Health Research UK Respiratory Bioscience Research Unit, Southampton General Hospital, Southampton, Hampshire, United KingdomElisabeth Aitken3National Institute of Health Research UK Respiratory Bioscience Research Unit, Southampton General Hospital, Southampton, Hampshire, United KingdomSumita Kerley1Respiratory Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, Hampshire, United KingdomRamesh Kurukulaaratchy4Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, United KingdomChristopher Grainge2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United KingdomRatko Djukanovic2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United KingdomAnoop Chauhan1Respiratory Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, Hampshire, United KingdomPeter Howarth2Clinical and Experimental Sciences, Faculty of Medicine, Southampton, Hampshire, United Kingdom
- Correlation of inflammatory markers of disease with sputum neutrophilia in severe asthmaBy Clair Barber, Laurie Lau, Scott Elliott, Jon Ward, Kerry Gove, Tom Brown, Hitasha Rupani, Tim Hinks, Ratko Djukanovic, Ramesh Kurukulaaratchy, Anoop Chauhan, Karl J. Staples and Peter HowarthClair Barber1NIHR Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, Hampshire United KingdomLaurie Lau2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomScott Elliott3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire United KingdomJon Ward2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomKerry Gove2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomTom Brown3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire United KingdomHitasha Rupani2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomTim Hinks2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomRatko Djukanovic2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomRamesh Kurukulaaratchy4Respiratory Medicine, University Hospital Southampton, NHS Foundation Trust, Southampton, Hampshire United KingdomAnoop Chauhan3Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, Hampshire United KingdomKarl J. Staples2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United KingdomPeter Howarth2Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, Hampshire United Kingdom
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