Joseph R. Arron
- Efficacy of an anti-IL13 monoclonal antibody, lebrikizumab, in adults with inadequately controlled asthma is enhanced in those with high periostin levelsBy Nicola A. Hanania, Robert F. Lemanske, Phillip E. Korenblat, Joseph R. Arron, Jeffrey M. Harris, Zheng Su, Sofia Mosesova, John G. Matthews, Merdad V. Parsey, Sean Bohen and Michelle M. FreemerNicola A. Hanania1Pulmonary & Critical Care Medicine, Baylor College of Medicine, Houston, TX, United StatesRobert F. Lemanske Jr.2Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United StatesPhillip E. Korenblat3Medicine, The Clinical Research Center, St. Louis, MO, United StatesJoseph R. Arron4Research & Early Development, Genentech, Inc., South San Francisco, CA, United StatesJeffrey M. Harris4Research & Early Development, Genentech, Inc., South San Francisco, CA, United StatesZheng Su5Bio Statistics, Genentech, Inc., South San Francisco, CA, United StatesSofia Mosesova5Bio Statistics, Genentech, Inc., South San Francisco, CA, United StatesJohn G. Matthews4Research & Early Development, Genentech, Inc., South San Francisco, CA, United StatesMerdad V. Parsey6Executive Office, 3-V Biosciences, Menlo Park, CA, United StatesSean Bohen4Research & Early Development, Genentech, Inc., South San Francisco, CA, United StatesMichelle M. Freemer4Research & Early Development, Genentech, Inc., South San Francisco, CA, United States
- Disconnect between sputum neutrophils and other measures of airway inflammation in asthmaBy Joseph R. Arron, David F. Choy, Michel Laviolette, Steven G. Kelsen, Ammar Hatab, Richard Leigh, Neil C. Thomson, Eugene R. Bleecker, Ron Olivenstein, Pedro C. Avila, Nizar N. Jarjour, Mario Castro, Gail M. Gauvreau, James T. Good, Joel N. Kline, Adel Mansur, Irvin Mayers, Liam G. Heaney, Qutayba Hamid and Jeffrey M. HarrisJoseph R. Arron1Genentech Research and Early Development, San Francisco, CADavid F. Choy1Genentech Research and Early Development, San Francisco, CAMichel Laviolette22IUCPQ, Université Laval, Quebec, QCSteven G. Kelsen3Dept of Medicine, Temple University School of Medicine, Philadelphia, PAAmmar Hatab4West Coast Clinical Trials LLC, Costa Mesa, CARichard Leigh5Faculty of Medicine, University of Calgary, Calgary, ABNeil C. Thomson66Institute of Infection, Immunity, and Inflammation, University of Glasgow, GlasgowEugene R. Bleecker7Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NCRon Olivenstein8Montréal Chest Institute, Montreal, QCPedro C. Avila9Dept of Medicine, Northwestern University Feinberg School of Medicine, Chicago, ILNizar N. Jarjour10Dept of Medicine, University of Wisconsin-Madison, Madison, WIMario Castro11Dept of Medicine, Washington University School of Medicine, St Louis, MOGail M. Gauvreau12Dept of Respirology, Faculty of Health Sciences, McMaster University, Hamilton ONJames T. Good13Dept of Medicine, National Jewish Health, Denver, COJoel N. Kline1414Dept of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USAAdel Mansur15Respiratory Dept, Birmingham Heartlands Hospital, BirminghamIrvin Mayers16Dept of Medicine, University of Alberta, Edmonton, ABLiam G. Heaney17Centre for Infection and Immunity, Queens University Belfast, Belfast, UKQutayba Hamid1818Meakins-Christie Laboratories, McGill University, Montreal, QC, CanadaJeffrey M. Harris1Genentech Research and Early Development, San Francisco, CA
- Disconnect between sputum neutrophils and other measures of airway inflammation in asthmaBy Joseph R. Arron, David F. Choy, Michel Laviolette, Steven G. Kelsen, Ammar Hatab, Richard Leigh, Neil C. Thomson, Eugene R. Bleecker, Ron Olivenstein, Pedro C. Avila, Nizar N. Jarjour, Mario Castro, Gail M. Gauvreau, James T. Good, Joel N. Kline, Adel Mansur, Irvin Mayers, Liam G. Heaney, Qutayba Hamid and Jeffrey M HarrisArticle | Published in 2013 in European Respiratory JournalJoseph R. Arron*Genentech Research and Early Development, South San Francisco, CA, USADavid F. Choy*Genentech Research and Early Development, South San Francisco, CA, USAMichel Laviolette#IUCPQ, Université Laval, Québec, QC, CanadaSteven G. Kelsen¶Dept of Medicine, Temple University School of Medicine, Philadelphia PA, USAAmmar Hatab+West Coast Clinical Trials LLC, Costa Mesa, CA, USARichard Leigh§Faculty of Medicine, University of Calgary, Calgary, AB, CanadaNeil C. ThomsonfInstitute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, UKEugene R. Bleecker**Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USARon Olivenstein##Montréal Chest Institute, Montréal, QC, CanadaPedro C. Avila¶¶Dept of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USANizar N. Jarjour++Dept of Medicine, University of Wisconsin-Madison, Madison, WI, USAMario Castro§§Dept of Medicine, Washington University School of Medicine, St. Louis, MO, USAGail M. GauvreauffDept of Respirology, Faculty of Health Sciences, McMaster University, Hamilton ON, CanadaJames T. Good***Dept of Medicine, National Jewish Health, Denver, COJoel N. Kline###Dept of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USAAdel Mansur¶¶¶Respiratory Dept, Birmingham Heartlands Hospital, Birmingham, UKIrvin Mayers+++Dept of Medicine, University of Alberta, Edmonton, AB, CanadaLiam G. Heaney§§§Centre for Infection and Immunity, Queens University Belfast, Belfast, UKQutayba HamidfffMeakins-Christie Laboratories, McGill University, Montréal, QC, CanadaJeffrey M Harris*Genentech Research and Early Development, South San Francisco, CA, USA
- LATE-BREAKING ABSTRACT: Serum IL-13 is a peripheral biomarker for Type 2 asthmaBy Fang Cai, David F. Choy, Jochen Brumm, Cecile Holweg, Alyssa Morimoto, Joseph R. Arron, John Matthews and Heleen ScheerensFang Cai1ITGR/OMNI Biomarker Development, Genentech Inc., South San Francisco, CA United StatesDavid F. Choy2ITGR Diagnostic Discovery, Genentech Inc., South San Francisco, CA United StatesJochen Brumm3Biostatistics, Genentech Inc., South San Francisco, CA United StatesCecile Holweg1ITGR/OMNI Biomarker Development, Genentech Inc., South San Francisco, CA United StatesAlyssa Morimoto1ITGR/OMNI Biomarker Development, Genentech Inc., South San Francisco, CA United StatesJoseph R. Arron4Immunology Research, Genentech Inc., South San Francisco, CA United StatesJohn Matthews5Immunology Product Development, Genentech Inc., South San Francisco, CA United StatesHeleen Scheerens1ITGR/OMNI Biomarker Development, Genentech Inc., South San Francisco, CA United States
- Bronchoalveolar lavage tryptase levels are correlated with type 2 airway inflammation in mild asthmaBy Guiquan Jia, Ashley Morando, Janet Jackman, Nirav Bhakta, John V. Fahy, Prescott G. Woodruff, Kelly Loyet, Tangsheng Yi and Joseph R. ArronGuiquan Jia1ITGR Diagnostics Discovery, Genentech Inc., South San Francisco, CA United StatesAshley Morando4Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA United StatesJanet Jackman3Immunology, Genentech Inc., South San Francisco, CA United StatesNirav Bhakta2Airway Clinical Research Center and General Clinical Research Center, University of California, San Francisco, San Francisco, CA United StatesJohn V. Fahy2Airway Clinical Research Center and General Clinical Research Center, University of California, San Francisco, San Francisco, CA United StatesPrescott G. Woodruff2Airway Clinical Research Center and General Clinical Research Center, University of California, San Francisco, San Francisco, CA United StatesKelly Loyet4Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA United StatesTangsheng Yi3Immunology, Genentech Inc., South San Francisco, CA United StatesJoseph R. Arron1ITGR Diagnostics Discovery, Genentech Inc., South San Francisco, CA United States
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The ERS Monograph is the quarterly book series from the European Respiratory Society. Each Monograph covers a specific area of respiratory medicine, providing in-depth reviews that give clinicians at all levels a concise, comprehensive guide to symptoms, diagnosis and treatment.
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